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NCT00002351 · ClinicalTrials.gov registry record · Phase 1
A Study of L-735,524 in HIV-Positive Children and Adolescents
A Phase 1 study of HIV Infections, sponsored by Merck Sharp & Dohme.
- Completed
- Registry status
- Phase 1
- Development phase
- 12
- Enrollment target
- 1
- Study location
NCT00002351: Completed Phase 1 study of HIV Infections, sponsored by Merck Sharp & Dohme.
NCT00002351 is a Phase 1 study of HIV Infections that has completed, run by Merck Sharp & Dohme. The registered enrollment target is 12 participants, below the 446-participant average among 542 other HIV Infections trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00002351, a Phase 1 study of HIV Infections, has completed, sponsored by Merck Sharp & Dohme.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 12 participants
- Enrollment target
- 1
- Study location
Study Summary
To evaluate the safety, tolerability, and plasma concentration profiles of indinavir sulfate ( MK-639; Crixivan ) in HIV-seropositive older children and adolescents. To compare the plasma concentration profile after the initial dose with data from a historical group of adults. To obtain preliminary data on antiviral activity of MK-639.
Conditions Studied
Interventions
- DRUG Indinavir sulfate
Study Locations (1)
New Jersey
- Merck & Co Inc - Whitehouse Station
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Phase | Phase 1 |
What the finished NCT00002351 record still lists
NCT00002351 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 446-participant average among 542 other HIV Infections trials with a reported enrollment target (97% lower).
The record links to 1 condition, with HIV Infections appearing as the primary indexed condition, and to 1 intervention - of which Indinavir sulfate is the first listed.
NCT00002351 reports a single indexed study location in New Jersey.
Frequently Asked Questions
What is clinical trial NCT00002351 about?
NCT00002351 is a clinical study titled "A Study of L-735,524 in HIV-Positive Children and Adolescents". To evaluate the safety, tolerability, and plasma concentration profiles of indinavir sulfate ( MK-639; Crixivan ) in HIV-seropositive older children and adolescents. To compare the plasma concentration profile after the initial dose with data from a historical group of adults. To obtain preliminary ...
What is the current status of trial NCT00002351?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 12 participants.
What conditions does trial NCT00002351 study?
This clinical trial studies the following conditions: HIV Infections.
What interventions are being tested in trial NCT00002351?
The interventions under investigation include: Indinavir sulfate (DRUG).
Who is sponsoring clinical trial NCT00002351?
This trial is sponsored by Merck Sharp & Dohme, which has 558 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00002351 being conducted?
This trial has 1 study location across New Jersey. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for HIV Infections
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00002351's enrollment target sits among peer trials
12 519th of 542 higher than 18 of 542 other HIV Infections trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other HIV Infections trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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