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NCT00001648 · ClinicalTrials.gov registry record
Structure of the Herpes Simplex Virus Receptor
A clinical trial of Herpes Simplex and Encephalitis, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).
- Completed
- Registry status
- 60
- Enrollment target
- 1
- Study location
NCT00001648: Completed study of Herpes Simplex and Encephalitis, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).
NCT00001648 is a study of Herpes Simplex and Encephalitis that has completed, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 60 participants, below the 1,709-participant average among 4 other Herpes Simplex trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00001648, a study of Herpes Simplex and Encephalitis, has completed, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).
- COMPLETED
- Registry status
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will examine the structure of the receptor molecule for the herpes simplex virus (HSV) and determine if the receptor's structure is related to susceptibility to infection with the virus. There are two types of herpes virus-HSV-1 and HSV-2. HSV-1 commonly causes cold sores, and HSV-2 usually causes genital herpes. The herpes virus enters (infects) cells through protein molecules on the cell's surface. This study will explore possible differences between the structure of the HSV receptor molecule in different people to understand better how infection occurs. The study will also look at proteins on white blood cells (Fc receptors, cytokines and mannose binding protein) that may influence the risk of infection with HSV. Information from this study may lead to new treatments to prevent HSV infection. People 18 years of age and older who are infected with HSV and people who are not infected with the virus may be eligible for this study. Participants will have blood drawn to confirm whether or not they have been infected with the virus. The blood sample will also be used to study the genes for the HSV receptor, Fc receptors, cytokines, mannose binding protein and related proteins on the white blood cells. No more than 40 milliliters (8 teaspoons) of blood will be drawn. Participants who are found to have antibodies to HSV-2 will be offered counseling and advice on practicing safe sex techniques to help prevent sexually transmitted diseases, including HSV-2 infection.
Conditions Studied
Study Locations (1)
Maryland
- National Institutes of Health Clinical Center, 9000 Rockville Pike - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 1997-08-20 |
| Est. Completion | 2010-04-13 |
What the finished NCT00001648 record still lists
NCT00001648 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 1,709-participant average among 4 other Herpes Simplex trials with a reported enrollment target (96% lower).
The record links to 5 conditions, with Herpes Simplex appearing as the primary indexed condition, and to 0 interventions.
NCT00001648 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT00001648 about?
NCT00001648 is a clinical study titled "Structure of the Herpes Simplex Virus Receptor". This study will examine the structure of the receptor molecule for the herpes simplex virus (HSV) and determine if the receptor's structure is related to susceptibility to infection with the virus. There are two types of herpes virus-HSV-1 and HSV-2. HSV-1 commonly causes cold sores, and HSV-2 usual...
What is the current status of trial NCT00001648?
This trial is currently completed. The enrollment target is 60 participants. The study started on 1997-08-20. Estimated completion is 2010-04-13.
What conditions does trial NCT00001648 study?
This clinical trial studies the following conditions: Herpes Simplex, Encephalitis, Skin Disease, Keratitis, Mouth Disease.
Who is sponsoring clinical trial NCT00001648?
This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00001648 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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