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NCT00001455 · ClinicalTrials.gov registry record
Iron Overload in African Americans
A clinical trial of Iron Overload and Hemochromatosis, sponsored by Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD).
- Completed
- Registry status
- 500
- Enrollment target
- 1
- Study location
NCT00001455: Completed study of Iron Overload and Hemochromatosis, sponsored by Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD).
NCT00001455 is a study of Iron Overload and Hemochromatosis that has completed, run by Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). The registered enrollment target is 500 participants, above the 216-participant average among 5 other Iron Overload trials with a reported enrollment target (131% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00001455, a study of Iron Overload and Hemochromatosis, has completed, sponsored by Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD).
- COMPLETED
- Registry status
- 500 participants
- Enrollment target
- 1
- Study location
Study Summary
Iron overload (hemochromatosis) is a condition which causes the intestines to take too much iron into the body from food or pills. The extra iron can build up in the liver, heart, joints, pancreas, sex organs, and other organs. Patients with iron overload can feel well initially, but the iron will eventually damage organs and may lead to an early death. The condition is believed to be passed down from generation to generation. Many studies have been conducted on the condition as it affects Caucasian Americans, few have addressed the condition in African Americans. Researchers believe it is important to find out as much as possible about the iron overload in African Americans. The goal of this study is to determine the pattern of inheritance of primary iron overload in African American families and to identify the genetic defect causing the condition. The study will use various tests from simple blood testing (transferritin saturation and serum ferritin levels) to complex genetic tests (segregation analysis and polymerase chain reaction \[PCR\]). The tests will help researchers deterimine iron levels in the blood, presence of antigens that may help trace inheritance, and detect changes in genes that are known to cause iron overload in Caucasians. The study may not directly benefit the patients participating in it. However, this study may lead to improved methods to diagnose iron overload in the African American population as a whole.
Conditions Studied
Study Locations (1)
Maryland
- National Institute of Child Health and Human Development (NICHD) - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 500 participants |
| Start Date | 1995-06 |
| Est. Completion | 2000-06 |
Sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)305 total trials
What the finished NCT00001455 record still lists
NCT00001455 is an observational study that tracks outcomes without assigning an intervention. The registered 500 participants enrollment target is mid-sized for trials with a published cap, above the 216-participant average among 5 other Iron Overload trials with a reported enrollment target (131% higher).
The record links to 2 conditions, with Iron Overload appearing as the primary indexed condition, and to 0 interventions.
NCT00001455 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT00001455 about?
NCT00001455 is a clinical study titled "Iron Overload in African Americans". Iron overload (hemochromatosis) is a condition which causes the intestines to take too much iron into the body from food or pills. The extra iron can build up in the liver, heart, joints, pancreas, sex organs, and other organs. Patients with iron overload can feel well initially, but the iron will e...
What is the current status of trial NCT00001455?
This trial is currently completed. The enrollment target is 500 participants. The study started on 1995-06. Estimated completion is 2000-06.
What conditions does trial NCT00001455 study?
This clinical trial studies the following conditions: Iron Overload, Hemochromatosis.
Who is sponsoring clinical trial NCT00001455?
This trial is sponsored by Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), which has 305 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00001455 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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