Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT00001245 · ClinicalTrials.gov registry record

Study of Patients With Strongyloides Stercoralis Infection

A clinical trial of HIV Infection and Nematode Infection, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

Completed
Registry status
650
Enrollment target
1
Study location

NCT00001245: Completed study of HIV Infection and Nematode Infection, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

NCT00001245 is a study of HIV Infection and Nematode Infection that has completed, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 650 participants, above the 234-participant average among 73 other HIV Infection trials with a reported enrollment target (178% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT00001245, a study of HIV Infection and Nematode Infection, has completed, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

COMPLETED
Registry status
650 participants
Enrollment target
1
Study location

Study Summary

This study will explore faster and easier ways to detect infection with the intestinal parasite Strongyloides stercoralis and learn more about the conditions under which it causes serious disease. Ordinarily, the Strongyloides helminth (type of intestinal worm) causes only few, if any, symptoms, but in people with weakened immunity it may be very serious, and even deadly. People between 5 and 80 years of age with known or suspected S. stercoralis infection, or infection with another helminth, such as filariasis, that might cause a cross-reaction with S. stercoralis may be eligible for this study. Participants found to be infected with S. stercoralis will be treated with ivermectin, thiabendazole, or albendazole. In addition, they will undergo the following tests and procedures: * Blood tests and stool samples: Samples will be collected before and after treatment to check general health status and immune function, and to look for parasites in stool. Up to 50 milliliters (10 teaspoons) of blood will be drawn in adults and up to 25 ml (5 teaspoons) in children. * Skin tests: A test similar to those used for tuberculosis and allergies will be conducted to determine if there is sensitization to products of the parasite. Such a test might be used as a rapid method to diagnose the infection. About three drops of several different antigens (proteins) are injected into the skin of the arm. After 15 to 20 minutes, the area is checked to see if a red spot has formed and, if so, the spot is measured.

Conditions Studied

HIV Infection Nematode Infection Strongyloidiasis

Study Locations (1)

Maryland

  • National Institutes of Health Clinical Center, 9000 Rockville Pike - Bethesda

Trial Details

FieldValue
Enrollment Target 650 participants
Start Date 1989-08
National Institute of Allergy and Infectious Diseases (NIAID)

2,006 total trials

What the finished NCT00001245 record still lists

NCT00001245 is an observational study that tracks outcomes without assigning an intervention. The registered 650 participants enrollment target is mid-sized for trials with a published cap, above the 234-participant average among 73 other HIV Infection trials with a reported enrollment target (178% higher).

The record links to 3 conditions, with HIV Infection appearing as the primary indexed condition, and to 0 interventions.

NCT00001245 reports a single indexed study location in Maryland.

Frequently Asked Questions

What is clinical trial NCT00001245 about?

NCT00001245 is a clinical study titled "Study of Patients With Strongyloides Stercoralis Infection". This study will explore faster and easier ways to detect infection with the intestinal parasite Strongyloides stercoralis and learn more about the conditions under which it causes serious disease. Ordinarily, the Strongyloides helminth (type of intestinal worm) causes only few, if any, symptoms, but...

What is the current status of trial NCT00001245?

This trial is currently completed. The enrollment target is 650 participants. The study started on 1989-08.

What conditions does trial NCT00001245 study?

This clinical trial studies the following conditions: HIV Infection, Nematode Infection, Strongyloidiasis.

Who is sponsoring clinical trial NCT00001245?

This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00001245 being conducted?

This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for HIV Infection

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT00001245's enrollment target sits among peer trials

650 5th of 73 higher than 69 of 73 other HIV Infection trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other HIV Infection trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT02934477 · 650 participants

    Prospective Assessment of Allogeneic Hematopoietic Cell Transplantation in Patients With Myelofibrosis

  • NCT04579120 · 650 participants

    Neuroimaging in Healthy Aging and Senile Dementia (HASD_IND)

  • NCT04875702 · 650 participants · Phase 4

    Treat-to-Target Serum Urate Versus Treat-to-Avoid Symptoms in Gout

  • NCT05046600 · 650 participants

    Registry of Arthrex Hand and Wrist Products

Similar registry start date

  • NCT05988463 · started 2027-01-01 · Phase 1

    Dose-Escalation Study of Artesunate Patients With IPF

  • NCT07219706 · started 2026-12-10 · NA

    Dietary Fiber and Time Restricted Eating

  • NCT02831335 · started 2026-12-01

    Technical Development of Multi-Parametric Renocerebral MRI

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

Related registry views

Source: ClinicalTrials.gov NCT00001245, the US trial registry maintained by the National Library of Medicine. NCT00001245 (mid enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.