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NCT00001245 · ClinicalTrials.gov registry record

Study of Patients With Strongyloides Stercoralis Infection

A clinical trial of HIV Infection and Nematode Infection, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

Completed
Registry status
650
Enrollment target
1
Study location

NCT00001245 is a study of HIV Infection and Nematode Infection that has completed, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 650 participants, above the 234-participant average among 73 other HIV Infection trials with a reported enrollment target (178% higher). The trial reports 1 study location across 1 state.

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The verdict

NCT00001245, a study of HIV Infection and Nematode Infection, has completed, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).

COMPLETED
Registry status
650 participants
Enrollment target
1
Study location

Study Summary

This study will explore faster and easier ways to detect infection with the intestinal parasite Strongyloides stercoralis and learn more about the conditions under which it causes serious disease. Ordinarily, the Strongyloides helminth (type of intestinal worm) causes only few, if any, symptoms, but in people with weakened immunity it may be very serious, and even deadly. People between 5 and 80 years of age with known or suspected S. stercoralis infection, or infection with another helminth, such as filariasis, that might cause a cross-reaction with S. stercoralis may be eligible for this study. Participants found to be infected with S. stercoralis will be treated with ivermectin, thiabendazole, or albendazole. In addition, they will undergo the following tests and procedures: * Blood tests and stool samples: Samples will be collected before and after treatment to check general health status and immune function, and to look for parasites in stool. Up to 50 milliliters (10 teaspoons) of blood will be drawn in adults and up to 25 ml (5 teaspoons) in children. * Skin tests: A test similar to those used for tuberculosis and allergies will be conducted to determine if there is sensitization to products of the parasite. Such a test might be used as a rapid method to diagnose the infection. About three drops of several different antigens (proteins) are injected into the skin of the arm. After 15 to 20 minutes, the area is checked to see if a red spot has formed and, if so, the spot is measured.

Study Locations (1)

Maryland

  • National Institutes of Health Clinical Center, 9000 Rockville Pike - Bethesda

Trial Details

FieldValue
Enrollment Target 650 participants
Start Date 1989-08

What the Registry Record Tells You About NCT00001245

The ClinicalTrials.gov registry entry for NCT00001245 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 650 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 234-participant average among 73 other HIV Infection trials with a reported enrollment target (178% higher). The listed sponsor is National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with HIV Infection appearing as the primary indexed condition, and to 0 interventions.

NCT00001245 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.

Frequently Asked Questions

What is clinical trial NCT00001245 about?

NCT00001245 is a clinical study titled "Study of Patients With Strongyloides Stercoralis Infection". This study will explore faster and easier ways to detect infection with the intestinal parasite Strongyloides stercoralis and learn more about the conditions under which it causes serious disease. Ordinarily, the Strongyloides helminth (type of intestinal worm) causes only few, if any, symptoms, but...

What is the current status of trial NCT00001245?

This trial is currently completed. The enrollment target is 650 participants. The study started on 1989-08.

What conditions does trial NCT00001245 study?

This clinical trial studies the following conditions: HIV Infection, Nematode Infection, Strongyloidiasis.

Who is sponsoring clinical trial NCT00001245?

This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT00001245 being conducted?

This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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