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NCT00001185 · ClinicalTrials.gov registry record
Study of "Post-Polio Syndrome"
A clinical trial of Poliomyelitis and Postpoliomyelitis Syndrome, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- Completed
- Registry status
- 360
- Enrollment target
- 1
- Study location
NCT00001185: Completed study of Poliomyelitis and Postpoliomyelitis Syndrome, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
NCT00001185 is a study of Poliomyelitis and Postpoliomyelitis Syndrome that has completed, run by National Institute of Neurological Disorders and Stroke (NINDS). The registered enrollment target is 360 participants. The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00001185, a study of Poliomyelitis and Postpoliomyelitis Syndrome, has completed, sponsored by National Institute of Neurological Disorders and Stroke (NINDS).
- COMPLETED
- Registry status
- 360 participants
- Enrollment target
- 1
- Study location
Study Summary
Polio or poliomyelitis is the disease caused by the poliovirus. The virus attacks cells in the spinal cord and causes symptoms of fever, sore throat, headache, vomiting, and stiffness of the neck. Patients with polio can have long-term weakness of muscles as a result of the damaged cells in the spinal cord. Occasionally, patients that recover from the disease can experience a relapse of muscle weakness. This can occur as long as 25-35 years after first having polio. The condition is called "post-polio syndrome". Not all nerve cells in the spinal cord are damaged by the poliovirus. Some nerve cells remain healthy and take over the work of the damaged cells. Researchers believe that the "post-polio syndrome" may be caused by failure of these overworked nerve cells. However, what causes these overworked nerve cells to disintegrate is unknown. The purpose of this study is to apply specific scientific tests to answer important questions about the causes and development of the post-polio syndrome. Researchers will investigate possible genetic, immunologic, and physiologic causes of the "post-polio syndrome". The study itself will not provide therapy for patients with the condition, but may lead to the development of therapies in the future.
Conditions Studied
Study Locations (1)
Maryland
- National Institute of Neurological Disorders and Stroke (NINDS) - Bethesda
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 360 participants |
| Start Date | 1982-06 |
| Est. Completion | 2003-05 |
What the finished NCT00001185 record still lists
NCT00001185 is an observational study that tracks outcomes without assigning an intervention. The registered 360 participants enrollment target is mid-sized for trials with a published cap.
The record links to 2 conditions, with Poliomyelitis appearing as the primary indexed condition, and to 0 interventions.
NCT00001185 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT00001185 about?
NCT00001185 is a clinical study titled "Study of "Post-Polio Syndrome"". Polio or poliomyelitis is the disease caused by the poliovirus. The virus attacks cells in the spinal cord and causes symptoms of fever, sore throat, headache, vomiting, and stiffness of the neck. Patients with polio can have long-term weakness of muscles as a result of the damaged cells in the spin...
What is the current status of trial NCT00001185?
This trial is currently completed. The enrollment target is 360 participants. The study started on 1982-06. Estimated completion is 2003-05.
What conditions does trial NCT00001185 study?
This clinical trial studies the following conditions: Poliomyelitis, Postpoliomyelitis Syndrome.
Who is sponsoring clinical trial NCT00001185?
This trial is sponsored by National Institute of Neurological Disorders and Stroke (NINDS), which has 567 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00001185 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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