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NCT00001150 · ClinicalTrials.gov registry record
Induction of Suction Blisters in Patients With Urticaria, Blistering Diseases, Inflammatory Dermatoses and Neoplastic Disorders, and in Normal Volunteers
A clinical trial, sponsored by National Cancer Institute (NCI).
- Completed
- Registry status
- 2,000
- Enrollment target
NCT00001150: Completed study, sponsored by National Cancer Institute (NCI).
NCT00001150 is a clinical trial that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 2,000 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00001150 has completed, sponsored by National Cancer Institute (NCI).
- COMPLETED
- Registry status
- 2,000 participants
- Enrollment target
Study Summary
The use of a suction blister apparatus has facilitated study of the immunologic capacity of human epidermal cells. We have been able to prepare purified populations of these cells after blister formation. Specifically, using the blister tops, we are able to enrich for epidermal Langerhans cells which are very potent stimulators in antigen presenting assays. Thus, this normal volunteer study provides an important source of fresh epidermal tissue from which we can study normal epidermal Langerhans cell function. In addition, we have recently used blister roofs in important experimental models of HIV-1 transmission. There is no other method available for assessing the biologic function of freshly isolated Langerhans cells without altering their milieu. It is a very safe and effective way to obtain human epidermal samples.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2,000 participants |
| Start Date | 1976-10 |
| Est. Completion | 2004-03 |
What the finished NCT00001150 record still lists
NCT00001150 is an observational study that tracks outcomes without assigning an intervention. Its 2,000 participants enrollment target places it among the larger protocols in the corpus.
The record links to 0 conditions, and to 0 interventions.
NCT00001150 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT00001150 about?
NCT00001150 is a clinical study titled "Induction of Suction Blisters in Patients With Urticaria, Blistering Diseases, Inflammatory Dermatoses and Neoplastic Disorders, and in Normal Volunteers". The use of a suction blister apparatus has facilitated study of the immunologic capacity of human epidermal cells. We have been able to prepare purified populations of these cells after blister formation. Specifically, using the blister tops, we are able to enrich for epidermal Langerhans cells whic...
What is the current status of trial NCT00001150?
This trial is currently completed. The enrollment target is 2,000 participants. The study started on 1976-10. Estimated completion is 2004-03.
Who is sponsoring clinical trial NCT00001150?
This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.
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