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NCT00001150 · ClinicalTrials.gov registry record

Induction of Suction Blisters in Patients With Urticaria, Blistering Diseases, Inflammatory Dermatoses and Neoplastic Disorders, and in Normal Volunteers

A clinical trial, sponsored by National Cancer Institute (NCI).

Completed
Registry status
2,000
Enrollment target

NCT00001150: Completed study, sponsored by National Cancer Institute (NCI).

NCT00001150 is a clinical trial that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 2,000 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00001150 has completed, sponsored by National Cancer Institute (NCI).

COMPLETED
Registry status
2,000 participants
Enrollment target

Study Summary

The use of a suction blister apparatus has facilitated study of the immunologic capacity of human epidermal cells. We have been able to prepare purified populations of these cells after blister formation. Specifically, using the blister tops, we are able to enrich for epidermal Langerhans cells which are very potent stimulators in antigen presenting assays. Thus, this normal volunteer study provides an important source of fresh epidermal tissue from which we can study normal epidermal Langerhans cell function. In addition, we have recently used blister roofs in important experimental models of HIV-1 transmission. There is no other method available for assessing the biologic function of freshly isolated Langerhans cells without altering their milieu. It is a very safe and effective way to obtain human epidermal samples.

Trial Details

FieldValue
Enrollment Target 2,000 participants
Start Date 1976-10
Est. Completion 2004-03

Sponsor

National Cancer Institute (NCI)

3,257 total trials

What the Registry Record Tells You About NCT00001150

The ClinicalTrials.gov registry entry for NCT00001150 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 2,000 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is National Cancer Institute (NCI), which has 3,257 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 0 interventions.

NCT00001150 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT00001150 about?

NCT00001150 is a clinical study titled "Induction of Suction Blisters in Patients With Urticaria, Blistering Diseases, Inflammatory Dermatoses and Neoplastic Disorders, and in Normal Volunteers". The use of a suction blister apparatus has facilitated study of the immunologic capacity of human epidermal cells. We have been able to prepare purified populations of these cells after blister formation. Specifically, using the blister tops, we are able to enrich for epidermal Langerhans cells whic...

What is the current status of trial NCT00001150?

This trial is currently completed. The enrollment target is 2,000 participants. The study started on 1976-10. Estimated completion is 2004-03.

Who is sponsoring clinical trial NCT00001150?

This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.