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NCT00001081 · ClinicalTrials.gov registry record · Phase 2
A Study of Nitazoxanide in Patients With AIDS and Diarrhea Caused by Cryptosporidium
A Phase 2 study of HIV Infections and Cryptosporidiosis, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).
- Completed
- Registry status
- Phase 2
- Development phase
- 60
- Enrollment target
- 1
- Study location
NCT00001081: Completed Phase 2 study of HIV Infections and Cryptosporidiosis, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).
NCT00001081 is a Phase 2 study of HIV Infections and Cryptosporidiosis that has completed, run by National Institute of Allergy and Infectious Diseases (NIAID). The registered enrollment target is 60 participants, below the 446-participant average among 542 other HIV Infections trials with a reported enrollment target (87% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00001081, a Phase 2 study of HIV Infections and Cryptosporidiosis, has completed, sponsored by National Institute of Allergy and Infectious Diseases (NIAID).
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
To determine the frequency of complete, marked, and partial clinical responses in patients with cryptosporidiosis treated with 6 weeks of NTZ versus 21 days of placebo. To determine the safety of NTZ in subjects with cryptosporidiosis. There is no proven therapy for cryptosporidiosis in persons with AIDS. Nitazoxanide appears to be a good candidate drug for further evaluation because of its effectiveness in preclinical models, the data from early clinical trials and its safety profile. Cooperation between clinical researchers and basic scientists in clinical trials of agents for HIV infection and its complications is a high priority for the ACTG, the NIAID, and the NIH. Thus, it is important to design a clinical trial of NTZ that includes cooperation with basic scientists.
Conditions Studied
Interventions
- DRUG Nitazoxanide
Study Locations (1)
Illinois
- Cook County Hosp. CORE Ctr. - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Est. Completion | 1998-09 |
| Phase | Phase 2 |
What the finished NCT00001081 record still lists
NCT00001081 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 446-participant average among 542 other HIV Infections trials with a reported enrollment target (87% lower).
The record links to 2 conditions, with HIV Infections appearing as the primary indexed condition, and to 1 intervention - of which Nitazoxanide is the first listed.
NCT00001081 reports a single indexed study location in Illinois.
Frequently Asked Questions
What is clinical trial NCT00001081 about?
NCT00001081 is a clinical study titled "A Study of Nitazoxanide in Patients With AIDS and Diarrhea Caused by Cryptosporidium". To determine the frequency of complete, marked, and partial clinical responses in patients with cryptosporidiosis treated with 6 weeks of NTZ versus 21 days of placebo. To determine the safety of NTZ in subjects with cryptosporidiosis. There is no proven therapy for cryptosporidiosis in persons wit...
What is the current status of trial NCT00001081?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 60 participants. Estimated completion is 1998-09.
What conditions does trial NCT00001081 study?
This clinical trial studies the following conditions: HIV Infections, Cryptosporidiosis.
What interventions are being tested in trial NCT00001081?
The interventions under investigation include: Nitazoxanide (DRUG).
Who is sponsoring clinical trial NCT00001081?
This trial is sponsored by National Institute of Allergy and Infectious Diseases (NIAID), which has 2,006 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00001081 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for HIV Infections
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00001081's enrollment target sits among peer trials
60 322nd of 542 higher than 205 of 542 other HIV Infections trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other HIV Infections trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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