NuVasive

Closed portfolio with a later-stage archive tilt

According to ClinicalTrials.gov-derived indexes, NuVasive sits in the top decile of US sponsors by registered trial count (#568 of 15,742 sponsors by registered trial count).

28 total trials none currently recruiting 27 completed later-stage tilt top decile by trial count

NuVasive: 28 sponsored US clinical trials, none currently recruiting.

NuVasive sponsors 28 registered US clinical trials on ClinicalTrials.gov, none currently recruiting, and 27 completed. 3 of these trials are in Phase 3-4 (later-stage) and 0 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Degenerative Disc Disease, with 4 trials.

Top-decile sponsor footprint

NuVasive ranks in the top decile of sponsors by registered trial count (#568 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

A 90/100

27 of 27 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (100.0%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Indexed trials (enrollment closed)

28 total, page 1 of 1

ACTIVE NOT RECRUITING

Long-term Assessment of the Safety and Performance of the NuVasive Simplify Disc

NCT05258435

COMPLETED

Retrospective Modulus ALIF Study

NCT05566704

COMPLETED

Post Approval Study Protocol for the Two Level Simplify® Cervical Artificial Disc

NCT04980378

COMPLETED

XLIF Decade Plate System Study

NCT04689880

COMPLETED NA

Post-Approval Study Protocol for the Simplify Cervical Artificial Disc

NCT04630626

COMPLETED

MSK Validation Study

NCT04422288

COMPLETED

Modulus in XLIF Study

NCT04418817

COMPLETED

MLX/XLX ACR Expandable Lumbar Interbody Implants

NCT04420143

COMPLETED NA

Investigation of the Two Level Simplify® Cervical Artificial Disc

NCT03123549

COMPLETED

Comprehensive Spinal Alignment Planning Study

NCT02606695

COMPLETED NA

Investigation of the Simplify® Cervical Artificial Disc

NCT02667067

COMPLETED

Advanced XLIF Monitoring Multicenter Study

NCT02272140

COMPLETED

Advanced XLIF Monitoring Pilot Study

NCT02192112

COMPLETED Phase 3

Post-Approval Clinical Trial of the PCM® Cervical Disc

NCT01905930

COMPLETED

A Prospective Non-concurrent Controlled Evaluation of Open and MAS® PLIF

NCT01640977

COMPLETED

Multimodality Neuromonitoring in XLIF

NCT01499680

COMPLETED

SpineTRACK Registry - Spinal Outcomes Registry

NCT01372592

COMPLETED

An Evaluation of Interlaminar Lumbar Instrumented (ILIF™)

NCT01019057

COMPLETED

XLIF® vs. MAS®TLIF for the Treatment of Symptomatic Lumbar Degenerative Spondylolisthesis With or Without Central Stenosis.

NCT01024699

COMPLETED Phase 3

XL TDR® eXtreme Lateral Total Disc Replacement for the Treatment of Lumbar Degenerative Disc Disease (DDD)

NCT00927238

COMPLETED

Osteocel® Plus in Posterior Lumbar Interbody Fusion (PLIF)

NCT00941980

COMPLETED

Osteocel® Plus in Transforaminal Lumbar Interbody Fusion (TLIF)

NCT00947583

COMPLETED

Osteocel® Plus in Anterior Lumbar Interbody Fusion (ALIF)

NCT00948831

COMPLETED

NeuroVision® Dynamic Screw Test Study

NCT01232517

COMPLETED

Osteocel® Plus in eXtreme Lateral Interbody Fusion (XLIF®)

NCT00948532

COMPLETED

Osteocel® Plus in Anterior Cervical Discectomy and Fusion (ACDF)

NCT00942045

COMPLETED NA

Evaluating The Safety and Effectiveness of The NeoDisc™ Versus ACDF in Subjects With Single-Level Cervical Disc Disease

NCT00478088

COMPLETED Phase 3

PCM Cervical Disc System

NCT00578812

How the NuVasive archive is shaped

28 indexed studies, none listed as recruiting (0% open); 27 completed (96%).

Phase mix: 3 late (III/IV) vs 0 early (I/II) (later-stage heavy).

Top condition: Degenerative Disc Disease (4 trials), 7 others listed.

How to read a closed sponsor archive

When recruiting_count is zero, the indexed set is completed or otherwise not open. Phase tilt still describes where archived studies sat on the investigational pathway. Re-check ClinicalTrials.gov before acting.

NuVasive: archived-pipeline peers nationwide

Peers matched on 28 indexed studies with no current recruiting: volume and archive shape, not condition overlap.

NuVasive sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0102030 0%5%10%15%20%25% Total trials Recruiting share NuVasiveAxsome TherapeuticsBenaroya Research InstituteCAMC Health SystemCTI BioPharma10xBio22nd Century Group23andMe3-C Institute for Social Development
NuVasive sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

NuVasive sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 28 archived trials

Sponsors with similar archive density (± trial count)

What to do with this NuVasive page

28 registered trials is a research-attention snapshot, not an endorsement of NuVasive or any single study.

  • None of NuVasive's trials are currently recruiting in this registry; that can change as new trials post, or check the broader research index. Browse research indexes
  • Degenerative Disc Disease is the condition NuVasive studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Degenerative Disc Disease trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

NuVasive pipeline card: 28 registered trials from official public datasets.Report a data error.