DeNova Research

Closed portfolio with an early-phase archive tilt

According to ClinicalTrials.gov-derived indexes, DeNova Research sits in the top decile of US sponsors by registered trial count (#801 of 15,742 sponsors by registered trial count).

18 total trials none currently recruiting 15 completed early-phase tilt top decile by trial count

DeNova Research: 18 sponsored US clinical trials, none currently recruiting.

DeNova Research sponsors 18 registered US clinical trials on ClinicalTrials.gov, none currently recruiting, and 15 completed. 2 of these trials are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Hand Rejuvination, with 1 trials.

Top-decile sponsor footprint

DeNova Research ranks in the top decile of sponsors by registered trial count (#801 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

F 48/100

15 of 18 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (83.3%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Indexed trials (enrollment closed)

18 total, page 1 of 1

COMPLETED Phase 3

Ethnic Lip Augmentation With Hyaluronic Acid Filler

NCT05730543

COMPLETED

First Impressions and Attractiveness Levels of Smiling Individuals With and Without a Mask

NCT05343559

COMPLETED NA

Non-Surgical Rhinoplasty Using PDO Threads

NCT04769427

COMPLETED Phase 1

Impact of Botox Treatment Into the Upper One Third of the Face an Area on Mood and Self -Appearance Satisfaction

NCT04439825

COMPLETED Phase 1

Restylane® Lyft Filler Injection for Hand Rejuvenation on First Impressions

NCT04162002

COMPLETED Phase 1

Effects of Restylane-L® Filler Injection for Non-Surgical Rhinoplasty

NCT04169308

TERMINATED NA

Oral Nutraceutical Supplement With Standardized Botanicals in Males With Self-Perceived Thinning Hair and Loss

NCT03709563

COMPLETED NA

Perioral Rejuvenation and Upper Lip Enhancement

NCT03273543

COMPLETED NA

A Study to Examine the Effects of Cosmeceutical Therapy in Subjects Undergoing Full Facial Rejuvenation

NCT02726451

COMPLETED NA

A Study to Assess the Efficacy of Skin Rejuvenation Therapy in Combination With Neurotoxin and Full Facial Filler Treatments

NCT02551562

COMPLETED NA

Assess the Impact of Lip Rejuvenation on Projected First Impressions and Mood Perceptions

NCT03241862

COMPLETED NA

A Study of Nutritional Supplementation in Altering Ecchymosis, Erythema and Health Outcomes Associated With Aesthetic Procedures

NCT01919359

COMPLETED Phase 2

A Study Evaluating the Efficacy and Safety of ARTISS Human Fibrin Sealant as Used in External Rhinoplasty

NCT01684020

COMPLETED Phase 2

A Double-Blinded, Randomized Placebo Controlled Pilot Study Comparing the Efficacy and Safety of IncobotulinumtoxinA Versus Saline Injections to the Cheek Region in Patients With Rosacea

NCT01614743

COMPLETED NA

Safety and Efficacy Study of Polydioxanone (PDS) Plates in Rhinoplasty

NCT01225250

COMPLETED Phase 4

Injectable Filler for Cheek Flattening

NCT01225354

TERMINATED NA

Botulinum Toxin A for Herpes Labialis

NCT01225341

TERMINATED Phase 2

Safety and Efficacy of the Use of Botox on Acne

NCT00765375

Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 3
Phase 3 1
Phase 4 1

How the DeNova Research early-phase archive is shaped

18 indexed studies, none listed as recruiting (0% open); 15 completed (83%).

Phase mix: 2 late (III/IV) vs 6 early (I/II) (early-phase heavy).

Top condition: Hand Rejuvination (1 trial), 3 others listed.

How to read a closed sponsor archive

When recruiting_count is zero, the indexed set is completed or otherwise not open. Phase tilt still describes where archived studies sat on the investigational pathway. Re-check ClinicalTrials.gov before acting.

DeNova Research: archived-pipeline peers nationwide

Peers matched on 18 indexed studies with no current recruiting: volume and archive shape, not condition overlap.

DeNova Research sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 05101520 0%10%20%30%40% Total trials Recruiting share DeNova ResearchADC Therapeutics S.A.Akros PharmaAO Clinical Investigation and Publishing DocumentationAO Innovation Translation Center10xBio22nd Century Group23andMe3-C Institute for Social Development
DeNova Research sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

DeNova Research sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 18 archived trials

Sponsors with similar archive density (± trial count)

What to do with this DeNova Research page

18 registered trials is a research-attention snapshot, not an endorsement of DeNova Research or any single study.

  • None of DeNova Research's trials are currently recruiting in this registry; that can change as new trials post, or check the broader research index. Browse research indexes
  • Hand Rejuvination is the condition DeNova Research studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Hand Rejuvination trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

DeNova Research pipeline card: 18 registered trials from official public datasets.Report a data error.