COMPASS Pathways

Closed portfolio with an early-phase archive tilt

According to ClinicalTrials.gov-derived indexes, COMPASS Pathways sits in the upper quartile of US sponsors by registered trial count (#1,604 of 15,742 sponsors by registered trial count).

8 total trials none currently recruiting 5 completed early-phase tilt upper quartile by trial count

COMPASS Pathways: 8 sponsored US clinical trials, none currently recruiting.

COMPASS Pathways sponsors 8 registered US clinical trials on ClinicalTrials.gov, none currently recruiting, and 5 completed. 2 of these trials are in Phase 3-4 (later-stage) and 5 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Treatment-Resistant Depression, with 2 trials.

Upper-quartile sponsor footprint

COMPASS Pathways sits in the upper quartile of the sponsor corpus (#1,604 of 15,742 sponsors by registered trial count) - denser than most sponsors, still short of the top-decile hubs.

Indexed trials (enrollment closed)

8 total, page 1 of 1

ACTIVE NOT RECRUITING Phase 3

Efficacy, Safety, and Tolerability of Two Administrations of COMP360 in Participants With TRD

NCT05711940
ACTIVE NOT RECRUITING Phase 2

A Phase II, Multicentre, Randomised, Double-blind, Controlled Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Efficacy of COMP360 in Participants With Recurrent Major Depressive Disorder

NCT05733546
ACTIVE NOT RECRUITING Phase 3

Efficacy, Safety, and Tolerability of COMP360 in Participants With TRD

NCT05624268
COMPLETED Phase 2

Efficacy and Safety of COMP360 Psilocybin Therapy in Anorexia Nervosa: a Proof-of-concept Study

NCT05481736
COMPLETED Phase 2

The Safety and Tolerability of COMP360 in Participants With Post-traumatic Stress Disorder

NCT05312151
COMPLETED Phase 2

The Safety and Efficacy Of Psilocybin as an Adjunctive Therapy in Participants With Treatment Resistant Depression

NCT04739865
COMPLETED

Long Term Follow Up Study to COMP 001 And COMP 003 Trials (P-TRD LTFU)

NCT04519957
COMPLETED Phase 2

The Safety and Efficacy of Psilocybin in Participants With Treatment Resistant Depression

NCT03775200

Phase Distribution

PhaseTrial count
Phase 2 5
Phase 3 2

Therapeutic Areas

Treatment-Resistant Depression 2
Major Depressive Disorder 1

How the COMPASS Pathways early-phase archive is shaped

8 indexed studies, none listed as recruiting (0% open); 5 completed (63%).

Phase mix: 2 late (III/IV) vs 5 early (I/II) (early-phase heavy).

Top condition: Treatment-Resistant Depression (2 trials), 1 other listed.

How to read a closed sponsor archive

When recruiting_count is zero, the indexed set is completed or otherwise not open. Phase tilt still describes where archived studies sat on the investigational pathway. Re-check ClinicalTrials.gov before acting.

COMPASS Pathways: archived-pipeline peers nationwide

Peers matched on 8 indexed studies with no current recruiting: volume and archive shape, not condition overlap.

COMPASS Pathways sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 051015 0%10%20%30%40% Total trials Recruiting share COMPASS PathwaysAB ScienceAbbott Point of CareAbeona TherapeuticsAcademisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)10xBio22nd Century Group23andMe3-C Institute for Social Development
COMPASS Pathways sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

COMPASS Pathways sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 8 archived trials

Sponsors with similar archive density (± trial count)

Related

Read our methodology - how this data is sourced, computed, and verified.

What to do with this COMPASS Pathways page

8 registered trials is a research-attention snapshot, not an endorsement of COMPASS Pathways or any single study.

  • None of COMPASS Pathways's trials are currently recruiting in this registry; that can change as new trials post, or check the broader research index. Browse research indexes
  • Treatment-Resistant Depression is the condition COMPASS Pathways studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Treatment-Resistant Depression trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

COMPASS Pathways pipeline card: 8 registered trials from official public datasets.Report a data error.