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NCT02456701 · ClinicalTrials.gov registry record · Phase 1

Enhancing Radioiodine Incorporation Into BRAF Mutant Thyroid Cancers With the Combination of Vemurafenib and KTN3379

A Phase 1 study, sponsored by Celldex Therapeutics.

Completed
Registry status
Phase 1
Development phase
7
Enrollment target

NCT02456701 is a Phase 1 study that has completed, run by Celldex Therapeutics. The registered enrollment target is 7 participants.

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The verdict

NCT02456701, a Phase 1 study, has completed, sponsored by Celldex Therapeutics.

COMPLETED
Registry status
Phase 1
Development phase
7 participants
Enrollment target

Study Summary

This is a patient pilot study testing the hypothesis that vemurafenib with the addition of KTN3379 can restore iodine incorporation in BRAF mutant (MUT), radioiodine-refractory (RAIR) thyroid cancer patients.

Interventions

  • DRUG vemurafenib
  • BIOLOGICAL KTN3379

Trial Details

FieldValue
Enrollment Target 7 participants
Start Date 2015-06
Est. Completion 2016-10-13
Phase Phase 1

Sponsor

Celldex Therapeutics

42 total trials

What the Registry Record Tells You About NCT02456701

The ClinicalTrials.gov registry entry for NCT02456701 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 7 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Celldex Therapeutics, which has 42 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which vemurafenib is the first listed.

NCT02456701 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02456701 about?

NCT02456701 is a clinical study titled "Enhancing Radioiodine Incorporation Into BRAF Mutant Thyroid Cancers With the Combination of Vemurafenib and KTN3379". This is a patient pilot study testing the hypothesis that vemurafenib with the addition of KTN3379 can restore iodine incorporation in BRAF mutant (MUT), radioiodine-refractory (RAIR) thyroid cancer patients.

What is the current status of trial NCT02456701?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 7 participants. The study started on 2015-06. Estimated completion is 2016-10-13.

What interventions are being tested in trial NCT02456701?

The interventions under investigation include: vemurafenib (DRUG), KTN3379 (BIOLOGICAL).

Who is sponsoring clinical trial NCT02456701?

This trial is sponsored by Celldex Therapeutics, which has 42 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.