Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Substance Dependence clinical trials
1 of 6 indexed Substance Dependence trials are currently recruiting.
Corpus placement: #2,866 of 28,707 conditions by registered trial count.
6 US clinical trials · 1 currently recruiting · #2,866 of 28,707 conditions by registered trial count
Substance Dependence: 6 US clinical trials tracked, 1 recruiting.
Substance Dependence is the subject of 6 registered US clinical trials on ClinicalTrials.gov, 1 of them currently open to new participants. The most active sponsor is Brown University, running 2 of these trials.
Enrollment posture brief
Registry condition substance-dependence
OPEN 1 | RECR 17% | LATE 0 | EARLY 0 | RANK #2866 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Acute Renal Failure (17% recruiting · 6 trials)
Substance Dependence lists 1 open slots (17% of 6 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Substance Dependence on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Substance Dependence is recruiting below its size-band peers.
1 of 6 indexed trials (16.7%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Substance Dependence research.
Brown University accounts for 2 of 6 trials (33.3%). 4 distinct sponsors appear on at least one study for this condition label.
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Typical Substance Dependence enrolment sits around 200 participants.
Median target enrolment is 200 among the 6 trials that report a genuine target (sentinel values excluded). 3 of those (50%) plan for fewer than 100 participants.
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Substance Dependence research is mostly interventional.
6 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
6 total, page 1 of 1
Pre-exposure Prophylaxis (PrEP) for Health
Brown University
NCT04430257
Continuing Care Following Drug Abuse Treatment: Linkage With Primary Care
Kaiser Permanente
NCT01621711
Harnessing Telemedicine to Improve Alcohol Use Disorder Outcomes in Primary Care Patients
University of Michigan
NCT05410561
Examining Feasibility and Acceptability of Telemedicine for Substance Use Disorder (SUD)
University of Michigan
NCT04768920
Developing a Telehealth Model to Improve Treatment Access for Rural Veterans With Substance Use Disorders
VA Office of Research and Development
NCT05348317
Group Therapy for Women Prisoners With Comorbid Substance Use and Depression
Brown University
NCT00606996
Phase Distribution
Phase data not available
Top Sponsors
Named interventions
Most-linked intervention names on Substance Dependence records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Substance Dependence trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Substance Dependence page
6 registered trials, 1 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 1 Substance Dependence trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Brown University sponsors the most Substance Dependence trials on record, review their full trial history before evaluating a specific study. See Brown University's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Substance Dependence condition card totals 6 registered trials; most-linked intervention Psychoeducation on co-occurring disorders (PSYCHOED); top US site state Michigan. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.