Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Spastic Paraplegia: early-phase trial registry
3 of 3 indexed Spastic Paraplegia trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #5,209 of 28,707 conditions by registered trial count.
3 US clinical trials · 3 currently recruiting · #5,209 of 28,707 conditions by registered trial count
Spastic Paraplegia: 3 US clinical trials tracked, 3 recruiting.
Spastic Paraplegia is the subject of 3 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is Elpida Therapeutics SPC, running 1 of these trials.
Enrollment posture brief
Registry condition spastic-paraplegia
OPEN 3 | RECR 100% | LATE 0 | EARLY 1 | RANK #5209 | SPON 1
Volume-matched condition peers
Nearest open-share peer: Aortic Arch Aneurysm (100% recruiting · 5 trials)
Spastic Paraplegia lists 3 open slots (100% of 3 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Spastic Paraplegia on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Spastic Paraplegia is recruiting above its size-band peers.
3 of 3 indexed trials (100%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
Open and recent trials
3 total, page 1 of 1
Natural History Study of Patients with HPDL Mutations
University of California, San Diego
NCT05848271
Extracorporeal Shockwave Therapy for Spasticity in People With Spinal Cord Injury
Kessler Foundation
NCT05432999
Melpida: Recombinant Adeno-associated Virus (serotype 9) Encoding a Codon Optimized Human AP4M1 Transgene (hAP4M1opt)
Elpida Therapeutics SPC
NCT05518188
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Spastic Paraplegia records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Spastic Paraplegia trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Spastic Paraplegia page
3 registered trials, 3 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 3 Spastic Paraplegia trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Elpida Therapeutics SPC sponsors the most Spastic Paraplegia trials on record, review their full trial history before evaluating a specific study. See Elpida Therapeutics SPC's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Spastic Paraplegia condition card totals 3 registered trials; most-linked intervention Extracorporeal Shockwave Therapy; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.