Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Post Operative Pain clinical trials
27 of 57 indexed Post Operative Pain trials are currently recruiting.
57 US clinical trials · 27 currently recruiting
Post Operative Pain is the subject of 57 registered US clinical trials on ClinicalTrials.gov, 27 of them currently open to new participants. 27 are in Phase 3-4 (later-stage) and 8 in Phase 1-2 (earlier-stage). The most active sponsor is Medical University of South Carolina, running 4 of these trials.
The research picture
Post Operative Pain has 57 registered US clinical trials, 27 of them open to new participants right now, about 47% of the total.
- 27
- recruiting participants now
- 47%
- of trials open to enrollment
- 27
- in Phase 3–4 (later-stage)
- 4
- top sponsor: Medical University of South Carolina
Active & Recent Trials
57 total, page 2 of 2
Opioid Education in Total Knee Arthroplasty
Hospital for Special Surgery, New York
NCT05593341
Effectiveness of Cannabidiol vs. Narcotics for Post Operative Pain Control in Elective Shoulder Arthroscopic Surgery
Foundation for Orthopaedic Research and Education
NCT05240755
Genicular Nerve Block for Total Knee Arthroplasty
Duke University
NCT03706313
Initial Local Anesthetic Dose With Continuous Interscalene Analgesia
Corewell Health East
NCT00672100
Effect of Post-Operative Anesthetics on Post-Operative Pain in Patients Receiving Endodontic Treatment
University of Washington
NCT05338671
Evaluation of the Effectiveness of tDCS in the Management of Perioperative Pain
Medical University of South Carolina
NCT01861587
Liposomal Bupivacaine for Post-operative Pain Control in Adolescent Bariatric Patients
Virginia Commonwealth University
NCT06077214
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 4 |
| Phase 2 | 4 |
| Phase 3 | 6 |
| Phase 4 | 21 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Post Operative Pain Trial Landscape
57 indexed Post Operative Pain studies · 27 recruiting (47%).
Phase mix: 27 late (III/IV) vs 8 early (I/II).
Top sponsor: Medical University of South Carolina (4 trials), 9 others listed. 7 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Post Operative Pain?
PlainTrial tracks 57 US clinical trials for Post Operative Pain, of which 27 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Post Operative Pain?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.