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Non-alcoholic Steatohepatitis clinical trials
3 of 13 indexed Non-alcoholic Steatohepatitis trials are currently recruiting.
13 US clinical trials · 3 currently recruiting
Non-alcoholic Steatohepatitis is the subject of 13 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 8 in Phase 1-2 (earlier-stage). The most active sponsor is Cirius Therapeutics, running 1 of these trials.
The research picture
Non-alcoholic Steatohepatitis has 13 registered US clinical trials, 3 of them open to new participants right now, about 23% of the total.
- 3
- recruiting participants now
- 23%
- of trials open to enrollment
- 1
- in Phase 3–4 (later-stage)
- 1
- top sponsor: Cirius Therapeutics
Active & Recent Trials
13 total, page 1 of 1
The Olmsted NAFLD Epidemiology Study (TONES)
Mayo Clinic
NCT04365855
Endoscopic Ultrasound Shear Wave Elastography in Patients With Non-alcoholic Fatty Liver Disease
Brigham and Women's Hospital
NCT05728697
Non-Alcoholic Fatty Liver Disease, the HEpatic Response to Oral Glucose, and the Effect of Semaglutide (NAFLD HEROES)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT03884075
Research Study on Whether Semaglutide Works in People With Non-alcoholic Steatohepatitis (NASH)
Novo Nordisk A/S
NCT04822181
A Study to Evaluate the Safety, Tolerability & Efficacy of MSDC-0602K in Patients With NASH
Cirius Therapeutics
NCT02784444
Emricasan, a Caspase Inhibitor, for Evaluation in Subjects With Non-Alcoholic Steatohepatitis (NASH) Fibrosis
Conatus Pharmaceuticals
NCT02686762
Effect of Patient Demographics, Comorbidities, and Medications on Severity of NASH Fibrosis
Methodist Health System
NCT05357352
A Study to Assess the Safety, Tolerability, Pharmacokinetics and Efficacy of EDP-305 in Subjects With Non-Alcoholic Steatohepatitis
Enanta Pharmaceuticals
NCT03421431
Safety and Tolerability Study of SHP626 in Overweight and Obese Adults
Mirum Pharmaceuticals
NCT02287779
Ezetimibe Versus Placebo in the Treatment of Non-alcoholic Steatohepatitis
University of California, San Diego
NCT01766713
Mobile Health Delivered Lifestyle Intervention Program in Patients With NASH
Milton S. Hershey Medical Center
NCT04872777
An Evaluation of the Safety and Efficacy of Nitazoxanide on Collagen Turnover in NASH Patients With Fibrosis
Pinnacle Clinical Research, P
NCT03656068
Saroglitazar Magnesium in the Treatment of Non-Alcoholic Steatohepatitis
Zydus Therapeutics
NCT03863574
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 7 |
| Phase 3 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Non-alcoholic Steatohepatitis Trial Landscape
13 indexed Non-alcoholic Steatohepatitis studies · 3 recruiting (23%).
Phase mix: 1 late (III/IV) vs 8 early (I/II).
Top sponsor: Cirius Therapeutics (1 trial), 9 others listed. 13 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Non-alcoholic Steatohepatitis?
PlainTrial tracks 13 US clinical trials for Non-alcoholic Steatohepatitis, of which 3 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Non-alcoholic Steatohepatitis?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.