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Intellectual Disability clinical trials
Every US clinical trial registered for Intellectual Disability — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
27 US clinical trials · 13 currently recruiting
The research picture
Intellectual Disability has 27 registered US clinical trials, 13 of them open to new participants right now — about 48% of the total.
- 13
- recruiting participants now
- 48%
- of trials open to enrollment
- 0
- in Phase 3–4 (later-stage)
- 3
- top sponsor: Boston Children's Hospital
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
Rett Syndrome Registry
International Rett Syndrome Foundation
NCT05432349
Future Planning and Well-Being for Individuals With Intellectual Disabilities and Family Caregivers
Northwell Health
NCT06065527
Longitudinal Study of Neurogenetic Disorders
Columbia University
NCT03492060
Physical Activity and Community EmPOWERment Project
University of North Carolina, Chapel Hill
NCT06740162
Characterization of Nociception Phenotype in Individuals With Intellectual Disability
National Institutes of Health Clinical Center (CC)
NCT05473429
Online Learning Module to Advance Research Related to People With Disabilities
Albert Einstein College of Medicine
NCT07220837
MEHMO Natural History and Biomarkers
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NCT06019182
Mental Health Crises in Youth With IDDs
Rady Pediatric Genomics & Systems Medicine Institute
NCT05471232
Cooking Skills to Improve Long-Term Weight Loss in Young Adults With Intellectual Disabilities
University of Kansas Medical Center
NCT06961591
Harnessing Communication Preferences
Joel E. Ringdahl
NCT07278544
Testing an Evidence-Based Supported Employment Model in Autistic Young Adults
University of California, Davis
NCT06829264
Early Augmentative and Alternative Communication (AAC) Intervention Delivered Via Hybrid Telehealth
Oregon Health and Science University
NCT05743439
Impact of Sulphonylureas on Neurodevelopmental Outcomes in KCNJ11-related Intermediate Developmental Delay, Epilepsy and Neonatal Diabetes (iDEND) Syndrome
Royal Devon and Exeter NHS Foundation Trust
NCT05751525
Improving the Health of Parents and Their Adolescent and Transition-age Youth With Intellectual and Developmental Disabilities
University of North Carolina, Chapel Hill
NCT05986305
Mapping the Genotype, Phenotype, and Natural History of Phelan-McDermid Syndrome
Boston Children's Hospital
NCT02461420
Autism Spectrum Disorder (ASD) and Intellectual Disability (ID) Determinants in Tuberous Sclerosis Complex (TSC)
Boston Children's Hospital
NCT02461459
Facing Your Fears: Adolescents With ASD and Intellectual Disability
University of Colorado, Denver
NCT05131425
We Walk Plus Study for Older Adults With Intellectual Disabilities
University of Illinois at Chicago
NCT04573530
Supporting the Health and Well-being of Children With Intellectual and Developmental Disability During COVID-19 Pandemic
Washington University School of Medicine
NCT04565509
Sedation Strategy and Cognitive Outcome After Critical Illness in Early Childhood
University of Pennsylvania
NCT02225041
Down Syndrome Memantine Follow-up Study
University Hospitals Cleveland Medical Center
NCT02304302
Fit Families Multisite
University of Wisconsin, Madison
NCT05451459
Effects of Guided Exercise on Functional Performance and Independence in Adults With Intellectual Disability
University of Delaware
NCT04616638
Mapping the Phenotype in Adults With Phelan-McDermid Syndrome
Boston Children's Hospital
NCT03426059
Effect of Sensory Adapted Dental Environment on Dental Anxiety of Children With Intellectual and Developmental Disabilities
Virginia Commonwealth University
NCT03218462
Parents as the Primary Sexuality Educators for Their Young Adults With Down Syndrome
Wake Forest University Health Sciences
NCT03135236
Expanding Interventions for Automatically Maintained SIB
University of Georgia
NCT06739616
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 2 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Intellectual Disability Trial Landscape
ClinicalTrials.gov lists 27 US studies indexed under Intellectual Disability, and 13 of those are currently open to recruitment — roughly 48% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Intellectual Disability shows 0 late-stage studies (Phase 3 and Phase 4 combined) alongside 1 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Intellectual Disability is led by Boston Children's Hospital with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 27 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Intellectual Disability?
PlainTrial tracks 27 US clinical trials for Intellectual Disability, of which 13 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Intellectual Disability?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.