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ClinicalTrials.gov 13 recruiting now early-phase tilt

Intellectual Disability: early-phase trial registry

13 of 27 indexed Intellectual Disability trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #598 of 28,707 conditions by registered trial count.

27 US clinical trials · 13 currently recruiting · #598 of 28,707 conditions by registered trial count

Intellectual Disability: 27 US clinical trials tracked, 13 recruiting.

Intellectual Disability is the subject of 27 registered US clinical trials on ClinicalTrials.gov, 13 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is Boston Children's Hospital, running 3 of these trials.

Enrollment posture brief

Registry condition intellectual-disability

OPEN 13 | RECR 48% | LATE 0 | EARLY 1 | RANK #598 | SPON 3

Nearest open-share peer: Merkel Cell Carcinoma (48% recruiting · 27 trials)

Alopecia Areata55.6%Intellectual Disability (thi…48%Acute Ischemic Stroke44.4%Adenocarcinoma25.9%Acne22.2%
Open-enrollment share among volume-matched conditions near Intellectual Disability

Intellectual Disability lists 13 open slots (48% of 27 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Intellectual Disability on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Intellectual Disability is recruiting above its size-band peers.

    13 of 27 indexed trials (48.1%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Intellectual Disability trials is spread across many organizations.

    Boston Children's Hospital accounts for 3 of 27 trials (11.1%). 24 distinct sponsors appear on at least one study for this condition label.

  3. Typical Intellectual Disability enrolment sits around 150 participants.

    Median target enrolment is 150 among the 27 trials that report a genuine target (sentinel values excluded). 12 of those (44.4%) plan for fewer than 100 participants.

  4. Intellectual Disability splits between interventional and observational designs.

    18 interventional and 9 observational studies make up this index (66.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 21

Open and recent trials

27 total, page 1 of 1

RECRUITING 3,000 participants

Rett Syndrome Registry

International Rett Syndrome Foundation

NCT05432349

RECRUITING NA 1,050 participants

Future Planning and Well-Being for Individuals With Intellectual Disabilities and Family Caregivers

Northwell Health

NCT06065527

RECRUITING 1,000 participants

Longitudinal Study of Neurogenetic Disorders

Columbia University

NCT03492060

RECRUITING NA 376 participants

Physical Activity and Community EmPOWERment Project

University of North Carolina, Chapel Hill

NCT06740162

RECRUITING NA 215 participants

Characterization of Nociception Phenotype in Individuals With Intellectual Disability

National Institutes of Health Clinical Center (CC)

NCT05473429

RECRUITING NA 200 participants

Online Learning Module to Advance Research Related to People With Disabilities

Albert Einstein College of Medicine

NCT07220837

RECRUITING 150 participants

MEHMO Natural History and Biomarkers

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NCT06019182

RECRUITING 150 participants

Mental Health Crises in Youth With IDDs

Rady Pediatric Genomics & Systems Medicine Institute

NCT05471232

RECRUITING NA 114 participants

Cooking Skills to Improve Long-Term Weight Loss in Young Adults With Intellectual Disabilities

University of Kansas Medical Center

NCT06961591

RECRUITING NA 60 participants

Harnessing Communication Preferences

Joel E. Ringdahl

NCT07278544

RECRUITING NA 60 participants

Testing an Evidence-Based Supported Employment Model in Autistic Young Adults

University of California, Davis

NCT06829264

RECRUITING NA 50 participants

Early Augmentative and Alternative Communication (AAC) Intervention Delivered Via Hybrid Telehealth

Oregon Health and Science University

NCT05743439

RECRUITING 21 participants

Impact of Sulphonylureas on Neurodevelopmental Outcomes in KCNJ11-related Intermediate Developmental Delay, Epilepsy and Neonatal Diabetes (iDEND) Syndrome

Royal Devon and Exeter NHS Foundation Trust

NCT05751525

ACTIVE NOT RECRUITING NA 406 participants

Improving the Health of Parents and Their Adolescent and Transition-age Youth With Intellectual and Developmental Disabilities

University of North Carolina, Chapel Hill

NCT05986305

ACTIVE NOT RECRUITING 205 participants

Mapping the Genotype, Phenotype, and Natural History of Phelan-McDermid Syndrome

Boston Children's Hospital

NCT02461420

ACTIVE NOT RECRUITING 205 participants

Autism Spectrum Disorder (ASD) and Intellectual Disability (ID) Determinants in Tuberous Sclerosis Complex (TSC)

Boston Children's Hospital

NCT02461459

ACTIVE NOT RECRUITING NA 73 participants

Facing Your Fears: Adolescents With ASD and Intellectual Disability

University of Colorado, Denver

NCT05131425

ACTIVE NOT RECRUITING NA 46 participants

We Walk Plus Study for Older Adults With Intellectual Disabilities

University of Illinois at Chicago

NCT04573530

COMPLETED NA 1,143 participants

Supporting the Health and Well-being of Children With Intellectual and Developmental Disability During COVID-19 Pandemic

Washington University School of Medicine

NCT04565509

COMPLETED 360 participants

Sedation Strategy and Cognitive Outcome After Critical Illness in Early Childhood

University of Pennsylvania

NCT02225041

COMPLETED Phase 2 160 participants

Down Syndrome Memantine Follow-up Study

University Hospitals Cleveland Medical Center

NCT02304302

COMPLETED NA 66 participants

Fit Families Multisite

University of Wisconsin, Madison

NCT05451459

COMPLETED NA 24 participants

Effects of Guided Exercise on Functional Performance and Independence in Adults With Intellectual Disability

University of Delaware

NCT04616638

COMPLETED 24 participants

Mapping the Phenotype in Adults With Phelan-McDermid Syndrome

Boston Children's Hospital

NCT03426059

COMPLETED NA 22 participants

Effect of Sensory Adapted Dental Environment on Dental Anxiety of Children With Intellectual and Developmental Disabilities

Virginia Commonwealth University

NCT03218462

COMPLETED NA 13 participants

Parents as the Primary Sexuality Educators for Their Young Adults With Down Syndrome

Wake Forest University Health Sciences

NCT03135236

COMPLETED NA 7 participants

Expanding Interventions for Automatically Maintained SIB

University of Georgia

NCT06739616

Phase Distribution

PhaseTrial count
Phase 2 1

Named interventions

Most-linked intervention names on Intellectual Disability records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Physical Activities & Activity Booklets (via FitFamilies app) Behavioral
1 trials
12-week FMS Intervention Other
1 trials
Sensory Adapted Dental Environment (SADE) Behavioral
1 trials
Fuzzy Cognitive Mapping Behavioral
1 trials
Enhanced Messaging Behavioral
1 trials
Standard Messaging Behavioral
1 trials
Parent training Behavioral
1 trials
A traditional RT intervention Behavioral
1 trials

US sites by state

Facility locations filed on Intellectual Disability trials. A trial with sites in several states counts in each.

Maryland 7 trials
Illinois 7 trials
California 7 trials
New York 6 trials
Massachusetts 6 trials
Texas 3 trials
Ohio 3 trials
North Carolina 3 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Intellectual Disability page

27 registered trials, 13 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Intellectual Disability condition card totals 27 registered trials; most-linked intervention Physical Activities & Activity Booklets (via FitFamilies app); top US site state Maryland. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.