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ClinicalTrials.gov 1 recruiting now later-stage tilt small index

Hyperpigmentation: later-stage trial registry

1 of 6 indexed Hyperpigmentation trials are currently recruiting, with more weight in Phase 3-4.

Corpus placement: #2,866 of 28,707 conditions by registered trial count.

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6 US clinical trials · 1 currently recruiting · #2,866 of 28,707 conditions by registered trial count

Hyperpigmentation: 6 US clinical trials tracked, 1 recruiting.

Hyperpigmentation is the subject of 6 registered US clinical trials on ClinicalTrials.gov, 1 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 0 in Phase 1-2 (earlier-stage). The most active sponsor is Integrative Skin Science and Research, running 2 of these trials.

Enrollment posture brief

Registry condition hyperpigmentation

OPEN 1 | RECR 17% | LATE 1 | EARLY 0 | RANK #2866 | SPON 2

Volume-matched condition peers

Nearest open-share peer: Acute Renal Failure (17% recruiting · 6 trials)

Acute Hypoxemic Respiratory 66.7%Abdominal Aortic Aneurysms50%Acupuncture50%Acute Lymphoblastic Leukemia50%Hyperpigmentation (this)17%
Open-enrollment share among volume-matched conditions near Hyperpigmentation

Hyperpigmentation lists 1 open slots (17% of 6 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Hyperpigmentation on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Hyperpigmentation is recruiting below its size-band peers.

    1 of 6 indexed trials (16.7%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Hyperpigmentation research.

    Integrative Skin Science and Research accounts for 2 of 6 trials (33.3%). 5 distinct sponsors appear on at least one study for this condition label.

  3. Most Hyperpigmentation trials plan to enrol fewer than 100 people.

    Median target enrolment is 28 among the 6 trials that report a genuine target (sentinel values excluded). 6 of those (100%) plan for fewer than 100 participants.

  4. Hyperpigmentation research is mostly interventional.

    5 interventional and 1 observational studies make up this index (83.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 41

Phase Distribution

PhaseTrial count
Phase 4 1

Top Sponsors

Integrative Skin Science and Research 2 trials
Sadick Research Group 1 trials
Albert Einstein College of Medicine 1 trials
Medstar Health Research Institute 1 trials
University of Texas Southwestern Medical Center 1 trials

Named interventions

Most-linked intervention names on Hyperpigmentation records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

vehicle Combination
1 trials
5% red maple leaf extract Combination
1 trials
1% red maple leaf extract in cream base Combination
1 trials
Hydroquinone Drug
1 trials
Herbal depigmenting agent (Epionce) Other
1 trials
MOXI Device
1 trials
Topical Cetyl Tranexamate Mesylate Other
1 trials
Sciton Halo Device
1 trials

US sites by state

Facility locations filed on Hyperpigmentation trials. A trial with sites in several states counts in each.

New York 2 trials
California 2 trials
Texas 1 trials
District of Columbia 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Related

Read our methodology - how this data is sourced, computed, and verified.

What to do with this Hyperpigmentation page

6 registered trials, 1 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Hyperpigmentation condition card totals 6 registered trials; most-linked intervention vehicle; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.