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Gut Microbiome clinical trials
Every US clinical trial registered for Gut Microbiome — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
23 US clinical trials · 16 currently recruiting
The research picture
Gut Microbiome has 23 registered US clinical trials, 16 of them open to new participants right now — about 70% of the total.
- 16
- recruiting participants now
- 70%
- of trials open to enrollment
- 1
- in Phase 3–4 (later-stage)
- 2
- top sponsor: Seeding
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
Fecal Microbiota Transplant National Registry
American Gastroenterological Association
NCT03325855
Flourish: Exploring the Early Infant Gut Microbiome
Seeding
NCT07333482
A Study to Explore the Role of Gut Flora in COVID-19 Infection
ProgenaBiome
NCT04359836
Early Avocado Exposure on Development and the Gut Microbiome in American Hispanic Infants
Arizona State University
NCT06876935
The Gut Microbiome and Serum Metabolites As a Biological Mechanism Underlying Pain in Kidney Transplantation
University of Illinois at Chicago
NCT06206486
The Path Study: Cognitive and Inflammation Targeted Gut-brain Interventions in Alcohol; Probiotics, Alcohol, Transcutaneous Vagus Nerve Stimulation, and HIV Study
University of Florida
NCT05090267
The Effect Cranberry-Based Products on the Female Microbiome
Ocean Spray Cranberries
NCT07109713
Curcumin and Retinal Study
Texas Tech University Health Sciences Center
NCT05774704
Effects of Mango or Low-Fat Cookie Consumption on Gut Health, and Its Relationship With Mental, Sexual and Skin Health
San Diego State University
NCT06800833
Enhanced Nutritional Optimization in LVAD Trial
Columbia University
NCT05655910
How a Single Workout Affects Gut Bugs in Women With Different Fitness Levels and Body Types
George Washington University
NCT06691100
Impact of Gut Microbiome on Metabolic and Bowel Function During the First Year After Spinal Cord Injury
University of Alabama at Birmingham
NCT05670288
Feasibility and Potential Efficacy of Herbs and Spices for Improving Dietary Quality in College Students: A Pilot Study
University of Nevada, Las Vegas
NCT07082348
Gut Microbiome and Treatment for Gynecological Cancer Patients Receiving Immunotherapy
Viome
NCT04957511
Understanding the Efficacy of Dietary Supplement on Fungal Mycobiota in Healthy Volunteers: A Pilot Study
Weill Medical College of Cornell University
NCT06433310
Garden-fresh Foods and Gut Microbiomes
University of Oregon
NCT06506786
Effects of Complementary Feeding on Infant Growth and Gut Health
University of Colorado, Denver
NCT05012930
Gut Microbe Composition, Exercise, and Breast Breast Cancer Survivors
University of Alabama at Birmingham
NCT04088708
Infant Restore: Efficacy of Microbiome Analysis and Education
Seeding
NCT06424691
Low Sugar Protein Pacing, Intermittent Fasting Diet in Men and Women
Skidmore College
NCT04327141
Salmon Intake and Gut Health in Adults
University of Colorado, Denver
NCT04792216
Yogurt and GI Health
USDA, Western Human Nutrition Research Center
NCT05931471
Fiber Blends and Gut Microbiota (FB)
Washington University School of Medicine
NCT04101344
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 4 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Gut Microbiome Trial Landscape
ClinicalTrials.gov lists 23 US studies indexed under Gut Microbiome, and 16 of those are currently open to recruitment — roughly 70% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Gut Microbiome shows 1 late-stage studies (Phase 3 and Phase 4 combined) alongside 1 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Gut Microbiome is led by Seeding with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 23 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Gut Microbiome?
PlainTrial tracks 23 US clinical trials for Gut Microbiome, of which 16 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Gut Microbiome?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.