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NCT01546454 · ClinicalTrials.gov registry record · NA
Relationship Between the Menstrual Cycle and Heart Disease in Women
A NA study of Coronary Heart Disease, sponsored by Oregon Health and Science University.
- Completed
- Registry status
- NA
- Development phase
- 5
- Enrollment target
- 1
- Study location
NCT01546454: Completed NA study of Coronary Heart Disease, sponsored by Oregon Health and Science University.
NCT01546454 is a NA study of Coronary Heart Disease that has completed, run by Oregon Health and Science University. The registered enrollment target is 5 participants, below the 1,488-participant average among 19 other Coronary Heart Disease trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01546454, a NA study of Coronary Heart Disease, has completed, sponsored by Oregon Health and Science University.
- COMPLETED
- Registry status
- NA
- Development phase
- 5 participants
- Enrollment target
- 1
- Study location
Study Summary
Women who have regular menstrual cycles have a lower risk of heart disease than men of the same age or women who no longer have menstrual cycles. The purpose of this study is to help determine why the menstrual cycle causes a lower risk of heart disease. The investigators believe that the hormones (estradiol and progesterone) produced during the menstrual cycle, as well as the normal processes occurring in the follicle and corpus luteum (transformed follicle), change levels of "good" and "bad" cholesterol in the blood-stream. These levels of good and bad cholesterol are an important risk factor for heart disease. Therefore, our goal is to determine what effects each of these factors (estradiol, progesterone, follicle, corpus luteum) have on the levels of good and bad cholesterol in the woman's bloodstream. As many women take birth control pills, which contain synthetic forms of estradiol and progesterone that block ovulation and development of a corpus luteum, the investigators also want to determine what effect one common type of birth control pill has on levels of good and bad cholesterol.
Conditions Studied
Interventions
- DRUG Progesterone
- DRUG Estradiol
- DRUG leuprolide acetate
- DRUG Ethinyl Estradiol-Levonorgestrel combination
Study Locations (1)
Oregon
- Oregon Health & Sciences University, Department of Obstetrics and Gynecology, Women's Health Research Unit - Portland
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 5 participants |
| Start Date | 2012-02 |
| Est. Completion | 2013-01 |
| Phase | NA |
What the finished NCT01546454 record still lists
NCT01546454 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 5 participants, a relatively small participant target, below the 1,488-participant average among 19 other Coronary Heart Disease trials with a reported enrollment target (100% lower).
The record links to 1 condition, with Coronary Heart Disease appearing as the primary indexed condition, and to 4 interventions - of which Progesterone is the first listed.
NCT01546454 reports a single indexed study location in Oregon.
Frequently Asked Questions
What is clinical trial NCT01546454 about?
NCT01546454 is a clinical study titled "Relationship Between the Menstrual Cycle and Heart Disease in Women". Women who have regular menstrual cycles have a lower risk of heart disease than men of the same age or women who no longer have menstrual cycles. The purpose of this study is to help determine why the menstrual cycle causes a lower risk of heart disease. The investigators believe that the hormones (...
What is the current status of trial NCT01546454?
This trial is currently completed. It is a NA study. The enrollment target is 5 participants. The study started on 2012-02. Estimated completion is 2013-01.
What conditions does trial NCT01546454 study?
This clinical trial studies the following conditions: Coronary Heart Disease.
What interventions are being tested in trial NCT01546454?
The interventions under investigation include: Progesterone (DRUG), Estradiol (DRUG), leuprolide acetate (DRUG), Ethinyl Estradiol-Levonorgestrel combination (DRUG).
Who is sponsoring clinical trial NCT01546454?
This trial is sponsored by Oregon Health and Science University, which has 546 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01546454 being conducted?
This trial has 1 study location across Oregon. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01546454's enrollment target sits among peer trials
5 20th of 19 the lowest of 19 other Coronary Heart Disease trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Coronary Heart Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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