Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Clinically Isolated Syndrome: later-stage trial registry
3 of 6 indexed Clinically Isolated Syndrome trials are currently recruiting, with more weight in Phase 3-4.
Corpus placement: #2,866 of 28,707 conditions by registered trial count.
6 US clinical trials · 3 currently recruiting · #2,866 of 28,707 conditions by registered trial count
Clinically Isolated Syndrome: 6 US clinical trials tracked, 3 recruiting.
Clinically Isolated Syndrome is the subject of 6 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 0 in Phase 1-2 (earlier-stage). The most active sponsor is Terry L. Wahls, running 2 of these trials.
Enrollment posture brief
Registry condition clinically-isolated-syndrome
OPEN 3 | RECR 50% | LATE 1 | EARLY 0 | RANK #2866 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Achalasia (50% recruiting · 8 trials)
Clinically Isolated Syndrome lists 3 open slots (50% of 6 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Clinically Isolated Syndrome on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Clinically Isolated Syndrome is recruiting above its size-band peers.
3 of 6 indexed trials (50%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Clinically Isolated Syndrome research.
Terry L. Wahls accounts for 2 of 6 trials (33.3%). 4 distinct sponsors appear on at least one study for this condition label.
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Typical Clinically Isolated Syndrome enrolment sits around 250 participants.
Median target enrolment is 250 among the 6 trials that report a genuine target (sentinel values excluded). 2 of those (33.3%) plan for fewer than 100 participants.
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Clinically Isolated Syndrome splits between interventional and observational designs.
3 interventional and 3 observational studies make up this index (50% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
6 total, page 1 of 1
MS-ResearchBiomarkerS
Cedars-Sinai Medical Center
NCT05204459
Autoimmune Intervention Mastery Course Study
Terry L. Wahls
NCT05057676
Pregnancy Registry, Infants, Serum/Milk Analysis (PRISMA)
University of California, San Francisco
NCT06940323
Clinically Isolated Syndrome and Relapsing-Remitting Multiple Sclerosis
Terry L. Wahls
NCT04009005
Impact of Ocrelizumab on Cerebrospinal Fluid Biomarkers at Multiple Sclerosis Onset
University of California, San Francisco
NCT04466150
A Study to Assess the Effectiveness and Safety of Mayzent in Chinese Patients With Relapsing Forms of Multiple Sclerosis
Novartis
NCT06395909
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 4 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Clinically Isolated Syndrome records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Clinically Isolated Syndrome trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Clinically Isolated Syndrome page
6 registered trials, 3 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 3 Clinically Isolated Syndrome trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Terry L. Wahls sponsors the most Clinically Isolated Syndrome trials on record, review their full trial history before evaluating a specific study. See Terry L. Wahls's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Clinically Isolated Syndrome condition card totals 6 registered trials; most-linked intervention Therapeutic diet and lifestyle; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.