Browse All Conditions

Explore 28,964 medical conditions with active and completed U.S. clinical trial data drawn from ClinicalTrials.gov, the U.S. National Institutes of Health public registry. According to ClinicalTrials.gov, the National Institutes of Health public registry maintained by the U.S. National Library of Medicine catalogs more than 500,000 clinical studies across over 220 countries since 1997, with the U.S. Food and Drug Administration Amendments Act (FDAAA) of 2007 requiring registration for most studies of FDA-regulated products. See our methodology for refresh cadence.

PlainTrial's condition directory indexes every disease, disorder, syndrome, and medical condition with at least one clinical study registered on ClinicalTrials.gov. Each entry links to a per-condition profile page showing recruiting trials, completed studies, phase distribution, sponsor mix, and geographic coverage. We use the MeSH-aligned condition names submitted by trial sponsors to the National Library of Medicine, so a condition you find here is the same condition a clinician would search on PubMed or a researcher would tag in a grant application.

Use the alphabetical index to browse the full list, or sort by trial volume to find conditions with the deepest active research pipelines. Conditions with a "Recruiting" count in the third column have at least one trial currently enrolling participants - click through to see locations and eligibility. Conditions with high trial counts but zero recruiting slots usually reflect a maturing pipeline (Phase 3 studies are enrollment-closed) or a condition where standard-of-care has shifted research focus to combination therapies and post-approval surveillance.

The directory is comprehensive but not equally deep across conditions. Rare diseases may show fewer than a handful of trials because patient populations are limited - this is a feature of clinical research, not an indexing gap on our end. Common conditions (cancer subtypes, diabetes, hypertension, depression) show dozens to hundreds of studies because they attract the broadest sponsor investment. Every number on this page comes directly from ClinicalTrials.gov; we do not manually edit counts, and we update from the NLM bulk-export on a regular cadence so what you see reflects the most recent registry state we have ingested.

Breast Cancer1251Healthy1096Obesity1057Prostate Cancer749Depression687Cancer621HIV Infections615Hypertension472Stroke456Non-Small Cell Lung Cancer450
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Treemap Treemap of 10 categories, sized proportional to value. Breast Cancer - 1,251 Breast Cancer 1,251 Healthy - 1,096 Healthy 1,096 Obesity - 1,057 Obesity 1,057 Prostate Cancer - 749 Prostate Cancer 749 Depression - 687 Depression 687 Cancer - 621 Cancer 621 HIV Infections - 615 HIV Infections 615 Hypertension - 472 Hypertension 472 Stroke - 456 Stroke 456 Non-Small Cell Lung Cancer - 450 Non-Small Cell Lu… 450 Non-Small Cell Lung Cancer - 450 Non-Small Cell Lu… 450
Condition Trials
Adult T Cell Leukemia 1
Adult T Cell Lymphoma 1
Adult T Cell Lymphoma (ATL) 1
Adult T-Cell Leukemia (ATL) 1
Adult T-cell Leukemia-Lymphoma 1
Adult T-cell Leukemia/Lymphoma 8
Adult Thoracic Procedures 2
Adult Unfavorable Prognosis Hodgkin Lymphoma 1
Adult Urological Procedures 2
Adult Women 1
Adult-Onset Diabetes Mellitus 1
Adult-Onset Glioma 1
Adults 4
Adults With Ulcerative Colitis 1
Adults With Variability in Their Mood 1
Adults Without Language Disorder 1
Adv Solid Malig - H&N SCC, ATM Pro / Def NSCLC, Gastric, Breast and Ovarian Cancer 1
Advance Care Planning 10
Advance Directive Completion 1
Advance Directives 2
Advanced (Stage IIIB/IV) Non-small Cell Lung Cancer (NSCLC) With MET Exon 14 (METex14) Skipping Alterations or MET Amplification 1
Advanced Acral Melanoma 1
Advanced Adenocarcinoma 3
Advanced Adenomas (AA) 1
Advanced Adrenal Gland Pheochromocytoma 1
Advanced Adult Hepatocellular Carcinoma 4
Advanced Adult Primary Liver Cancer 8
Advanced Alveolar Soft Part Sarcoma 1
Advanced Anal Carcinoma 1
Advanced and Metastatic Breast Cancer 1
Advanced Angiosarcoma 1
Advanced Basal Cell Carcinoma 1
Advanced Bile Duct Carcinoma 2
Advanced Biliary Tract Cancer 3
Advanced Biliary Tract Carcinoma 5
Advanced Bladder Cancer 1
Advanced Bladder Carcinoma 2
Advanced Bladder Urothelial Carcinoma 2
Advanced BRAF Mutant Cancers 1
Advanced Breast Cancer 29
Advanced Breast Cancer Stage IV 1
Advanced Breast Cancerv 1
Advanced Breast Carcinoma 11
Advanced Cancer 123
Advanced Cancers 11
Advanced Cancers of the Prostate 1
Advanced Carcinoid Tumor 2
Advanced CCNE1-amplified Solid Tumors 2
Advanced Cervical Adenocarcinoma 2
Advanced Cervical Adenosquamous Carcinoma 1