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NCT07692217 · ClinicalTrials.gov registry record

TG-INSIGHT With Joint POCUS, Hemostatic Potential in Patients With Severe Hemophilia A on Novel Replacement and Substitution FVIII Therapies

A clinical trial, sponsored by University of Texas Southwestern Medical Center.

Not yet
Registry status
60
Enrollment target

NCT07692217: Clinical Trial study, sponsored by University of Texas Southwestern Medical Center.

NCT07692217 is a clinical trial that has not yet begun recruiting, run by University of Texas Southwestern Medical Center. The registered enrollment target is 60 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07692217 has not yet begun recruiting, sponsored by University of Texas Southwestern Medical Center.

NOT YET RECRUITING
Registry status
60 participants
Enrollment target

Study Summary

This is an observational research study to find out if there is a difference in the way children with moderate or severe hemophilia A, treated on two different types of factor replacement, form a clot and also evaluate if they develop tiny bleeds within the joint and subsequently early joint changes when receiving extended half-life factor VIII.

Primary Outcome

To determine and compare in vivo thrombin generation parameters; endogenous thrombin potential (ETP) and peak thrombin (PT) for patients on efanesoctocog alfa or emicizumab

Interventions

  • DRUG Half-life factor VIII based replacement therapy
  • DRUG Non-FVIII based replacement therapy

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2026-07
Est. Completion 2033-05

What is known before NCT07692217 opens enrollment

NCT07692217 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 60 participants, a relatively small participant target.

The record links to 0 conditions, and to 2 interventions - of which Half-life factor VIII based replacement therapy is the first listed.

NCT07692217 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07692217 about?

NCT07692217 is a clinical study titled "TG-INSIGHT With Joint POCUS, Hemostatic Potential in Patients With Severe Hemophilia A on Novel Replacement and Substitution FVIII Therapies". This is an observational research study to find out if there is a difference in the way children with moderate or severe hemophilia A, treated on two different types of factor replacement, form a clot and also evaluate if they develop tiny bleeds within the joint and subsequently early joint changes...

What is the current status of trial NCT07692217?

This trial is currently not yet recruiting. The enrollment target is 60 participants. The study started on 2026-07. Estimated completion is 2033-05.

What interventions are being tested in trial NCT07692217?

The interventions under investigation include: Half-life factor VIII based replacement therapy (DRUG), Non-FVIII based replacement therapy (DRUG).

Who is sponsoring clinical trial NCT07692217?

This trial is sponsored by University of Texas Southwestern Medical Center, which has 837 total clinical trials registered on ClinicalTrials.gov.

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Source: ClinicalTrials.gov NCT07692217, the US trial registry maintained by the National Library of Medicine. NCT07692217 (small enrollment · none site footprint · not yet recruiting) retrieved and formatted by PlainTrial, see methodology.