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NCT07689773 · ClinicalTrials.gov registry record · Phase 2
Study of Chemosensory Enhancement Through Neuromodulation Training (SCENT): Open Label
A Phase 2 study, sponsored by Medical University of South Carolina.
- Not yet
- Registry status
- Phase 2
- Development phase
- 60
- Enrollment target
NCT07689773: Clinical Trial Phase 2 study, sponsored by Medical University of South Carolina.
NCT07689773 is a Phase 2 study that has not yet begun recruiting, run by Medical University of South Carolina. The registered enrollment target is 60 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (55% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07689773, a Phase 2 study, has not yet begun recruiting, sponsored by Medical University of South Carolina.
- NOT YET RECRUITING
- Registry status
- Phase 2
- Development phase
- 60 participants
- Enrollment target
Study Summary
Smell dysfunction significantly impacts quality of life and safety, with limited effective treatments. This open-label study evaluates the preliminary efficacy of combining non-invasive trigeminal nerve stimulation (TNS) with standard smell training (ST) to improve olfactory function. Participants will complete 8 weeks of at-home treatment and attend three in-person visits for assessment. Improvements in smell, mood, sleep, and quality of life will be measured.
Primary Outcome
Sniffin' Sticks (Bughardt Messtechnik, Wedel Germany) will be used to determine odor threshold (T), odor discrimination (D), and odor identification (I), each on 16-point scales, and summed for a total TDI score. Higher scores indicate better function.
Interventions
- COMBINATION_PRODUCT Trigeminal Nerve Stimulation-enhanced Smell Training
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2026-07-08 |
| Est. Completion | 2028-06-30 |
| Phase | Phase 2 |
What is known before NCT07689773 opens enrollment
NCT07689773 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (55% lower).
The record links to 0 conditions, and to 1 intervention - of which Trigeminal Nerve Stimulation-enhanced Smell Training is the first listed.
NCT07689773 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07689773 about?
NCT07689773 is a clinical study titled "Study of Chemosensory Enhancement Through Neuromodulation Training (SCENT): Open Label". Smell dysfunction significantly impacts quality of life and safety, with limited effective treatments. This open-label study evaluates the preliminary efficacy of combining non-invasive trigeminal nerve stimulation (TNS) with standard smell training (ST) to improve olfactory function. Participants w...
What is the current status of trial NCT07689773?
This trial is currently not yet recruiting. It is a Phase 2 study. The enrollment target is 60 participants. The study started on 2026-07-08. Estimated completion is 2028-06-30.
What interventions are being tested in trial NCT07689773?
The interventions under investigation include: Trigeminal Nerve Stimulation-enhanced Smell Training (COMBINATION_PRODUCT).
Who is sponsoring clinical trial NCT07689773?
This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07689773's enrollment target sits among peer trials
60 1027th of 2000 higher than 868 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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