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NCT07689227 · ClinicalTrials.gov registry record · NA
Closed-Loop Vagus Nerve Stimulation (CLV) for Recovery of Gait
A NA study, sponsored by The University of Texas at Dallas.
- Not yet
- Registry status
- NA
- Development phase
- 20
- Enrollment target
NCT07689227: Clinical Trial NA study, sponsored by The University of Texas at Dallas.
NCT07689227 is a NA study that has not yet begun recruiting, run by The University of Texas at Dallas. The registered enrollment target is 20 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07689227, a NA study, has not yet begun recruiting, sponsored by The University of Texas at Dallas.
- NOT YET RECRUITING
- Registry status
- NA
- Development phase
- 20 participants
- Enrollment target
Study Summary
The purpose of this study is to evaluate the safety, feasibility, and preliminary effectiveness of the ReWire system, which delivers vagus nerve stimulation (VNS) paired with lower limb rehabilitation to improve gait in individuals with mobility impairments resulting from chronic, incomplete spinal cord injury (SCI).
Primary Outcome
Safety of the ReWire system will be assessed by documenting the nature, frequency, severity, and relatedness of adverse events associated with the device, including those attributable to device implantation, stimulation delivery, and rehabilitation procedures.
Interventions
- DEVICE Sham
- DEVICE CLV
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2026-09-30 |
| Est. Completion | 2028-12 |
| Phase | NA |
What is known before NCT07689227 opens enrollment
NCT07689227 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 2 interventions - of which Sham is the first listed.
NCT07689227 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07689227 about?
NCT07689227 is a clinical study titled "Closed-Loop Vagus Nerve Stimulation (CLV) for Recovery of Gait". The purpose of this study is to evaluate the safety, feasibility, and preliminary effectiveness of the ReWire system, which delivers vagus nerve stimulation (VNS) paired with lower limb rehabilitation to improve gait in individuals with mobility impairments resulting from chronic, incomplete spinal ...
What is the current status of trial NCT07689227?
This trial is currently not yet recruiting. It is a NA study. The enrollment target is 20 participants. The study started on 2026-09-30. Estimated completion is 2028-12.
What interventions are being tested in trial NCT07689227?
The interventions under investigation include: Sham (DEVICE), CLV (DEVICE).
Who is sponsoring clinical trial NCT07689227?
This trial is sponsored by The University of Texas at Dallas, which has 50 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07689227's enrollment target sits among peer trials
20 1768th of 2000 higher than 140 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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