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NCT07685717 · ClinicalTrials.gov registry record · Phase 2
Pirtobrutinib for the Treatment of Elderly Patients With Chronic Lymphocytic Leukemia
A Phase 2 study, sponsored by Jennifer Woyach.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 50
- Enrollment target
NCT07685717: Recruiting Phase 2 study, sponsored by Jennifer Woyach.
NCT07685717 is a Phase 2 study that is actively recruiting participants, run by Jennifer Woyach. The registered enrollment target is 50 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (62% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07685717, a Phase 2 study, is actively recruiting participants, sponsored by Jennifer Woyach.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 50 participants
- Enrollment target
Study Summary
This phase II trial studies how well pirtobrutinib works in treating elderly patients with chronic lymphocytic leukemia (CLL). Bruton tyrosine kinase (BTK) inhibitors such as ibrutinib, acalabrutinib, and zanubrutinib work by blocking the action of the BTK protein that signals cancer cells to multiply. These are very effective, tolerable, and commonly used to treat people with CLL, but they may lead to drug resistance over time. Pirtobrutinib, also a BTK inhibitor, may work better in treating elderly patients with CLL.
Primary Outcome
Will be calculated among all evaluable patients. The rates will be provided together with 95% exact confidence intervals.
Interventions
- PROCEDURE Biospecimen Collection
- PROCEDURE Bone Marrow Aspiration
- PROCEDURE Bone Marrow Biopsy
- PROCEDURE Computed Tomography
- OTHER Electronic Health Record Review
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2026-08-01 |
| Est. Completion | 2027-12-31 |
| Phase | Phase 2 |
What NCT07685717 shows while recruiting
NCT07685717 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (62% lower).
The record links to 0 conditions, and to 5 interventions - of which Biospecimen Collection is the first listed.
NCT07685717 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07685717 about?
NCT07685717 is a clinical study titled "Pirtobrutinib for the Treatment of Elderly Patients With Chronic Lymphocytic Leukemia". This phase II trial studies how well pirtobrutinib works in treating elderly patients with chronic lymphocytic leukemia (CLL). Bruton tyrosine kinase (BTK) inhibitors such as ibrutinib, acalabrutinib, and zanubrutinib work by blocking the action of the BTK protein that signals cancer cells to multip...
What is the current status of trial NCT07685717?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 50 participants. The study started on 2026-08-01. Estimated completion is 2027-12-31.
What interventions are being tested in trial NCT07685717?
The interventions under investigation include: Biospecimen Collection (PROCEDURE), Bone Marrow Aspiration (PROCEDURE), Bone Marrow Biopsy (PROCEDURE), Computed Tomography (PROCEDURE), Electronic Health Record Review (OTHER).
Who is sponsoring clinical trial NCT07685717?
This trial is sponsored by Jennifer Woyach, which has 6 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07685717's enrollment target sits among peer trials
50 1195th of 2000 higher than 740 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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