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NCT07679607 · ClinicalTrials.gov registry record · Phase 2

GCC 2545- Improving Post-Radiotherapy Respiratory Function Through Sparing Serial and Parallel Components in the Lung

A Phase 2 study, sponsored by University of Maryland, Baltimore.

Not yet
Registry status
Phase 2
Development phase
70
Enrollment target

NCT07679607 is a Phase 2 study that has not yet begun recruiting, run by University of Maryland, Baltimore. The registered enrollment target is 70 participants.

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The verdict

NCT07679607, a Phase 2 study, has not yet begun recruiting, sponsored by University of Maryland, Baltimore.

NOT YET RECRUITING
Registry status
Phase 2
Development phase
70 participants
Enrollment target

Study Summary

Decreased respiratory function is a common side effect experienced by non-small cell lung cancer (NSCLC) patients who receive radiation therapy. In current clinical practice when treating cancerous lesions in the lung, it is not standard to explicitly try and avoid excessive radiation dose and therefore radiation injury to smaller airways. However, because of this patients may obtain damage to an airway segment can cause downstream regions in the lung to lose their "supply line" and, therefore, cause patients to lose the ability to exchange oxygen with the blood. The purpose of this clinical trial is to systematically compare post-treatment lung function of those who receive regular clinical radiation therapy (standard of care \[SoC\]) versus those who receive the airway-sparing radiation therapy regimen. The investigators hope to show that, by preserving airways and connected lung regions, participants will be able to retain a larger amount of their lung function, which will have a direct, positive impact on their post-treatment quality of life.

Interventions

  • RADIATION SOC Radiation Treatment Planning
  • RADIATION INSPIRE Radiation Treatment Planning

Trial Details

FieldValue
Enrollment Target 70 participants
Start Date 2026-08
Est. Completion 2030-08
Phase Phase 2

Sponsor

University of Maryland, Baltimore

560 total trials

What the Registry Record Tells You About NCT07679607

The ClinicalTrials.gov registry entry for NCT07679607 describes a study currently listed as not yet recruiting, categorized as Phase 2. The registered enrollment target is 70 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Maryland, Baltimore, which has 560 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which SOC Radiation Treatment Planning is the first listed.

NCT07679607 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT07679607 about?

NCT07679607 is a clinical study titled "GCC 2545- Improving Post-Radiotherapy Respiratory Function Through Sparing Serial and Parallel Components in the Lung". Decreased respiratory function is a common side effect experienced by non-small cell lung cancer (NSCLC) patients who receive radiation therapy. In current clinical practice when treating cancerous lesions in the lung, it is not standard to explicitly try and avoid excessive radiation dose and there...

What is the current status of trial NCT07679607?

This trial is currently not yet recruiting. It is a Phase 2 study. The enrollment target is 70 participants. The study started on 2026-08. Estimated completion is 2030-08.

What interventions are being tested in trial NCT07679607?

The interventions under investigation include: SOC Radiation Treatment Planning (RADIATION), INSPIRE Radiation Treatment Planning (RADIATION).

Who is sponsoring clinical trial NCT07679607?

This trial is sponsored by University of Maryland, Baltimore, which has 560 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.