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NCT07668635 · ClinicalTrials.gov registry record · Phase 1

Cannabis Effects on Opioid Self-Administration

A Phase 1 study, sponsored by Shanna Babalonis, PhD.

Not yet
Registry status
Phase 1
Development phase
30
Enrollment target

NCT07668635: Clinical Trial Phase 1 study, sponsored by Shanna Babalonis, PhD.

NCT07668635 is a Phase 1 study that has not yet begun recruiting, run by Shanna Babalonis, PhD. The registered enrollment target is 30 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (50% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07668635, a Phase 1 study, has not yet begun recruiting, sponsored by Shanna Babalonis, PhD.

NOT YET RECRUITING
Registry status
Phase 1
Development phase
30 participants
Enrollment target

Study Summary

The study will enroll participants with opioid use disorder and participants will reside at the University of Kentucky Hospital for this 6-week inpatient trial. During this time, double-blind doses of cannabis and opioids will be administered. The goal of the project is to determine if cannabis can alter the drive/desire to take opioids.

Primary Outcome

Number of drug-choice trials completed for intranasal opioid agonists during self-administration sessions.

Interventions

  • DRUG Cannabis
  • DRUG Placebo Cannabis
  • DRUG Intranasal Opioid Agonist
  • DRUG Oral Opioid Agonist

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2026-07-30
Est. Completion 2031-07-30
Phase Phase 1
Shanna Babalonis, PhD

6 total trials

What is known before NCT07668635 opens enrollment

NCT07668635 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (50% lower).

The record links to 0 conditions, and to 4 interventions - of which Cannabis is the first listed.

NCT07668635 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07668635 about?

NCT07668635 is a clinical study titled "Cannabis Effects on Opioid Self-Administration". The study will enroll participants with opioid use disorder and participants will reside at the University of Kentucky Hospital for this 6-week inpatient trial. During this time, double-blind doses of cannabis and opioids will be administered. The goal of the project is to determine if cannabis can ...

What is the current status of trial NCT07668635?

This trial is currently not yet recruiting. It is a Phase 1 study. The enrollment target is 30 participants. The study started on 2026-07-30. Estimated completion is 2031-07-30.

What interventions are being tested in trial NCT07668635?

The interventions under investigation include: Cannabis (DRUG), Placebo Cannabis (DRUG), Intranasal Opioid Agonist (DRUG), Oral Opioid Agonist (DRUG).

Who is sponsoring clinical trial NCT07668635?

This trial is sponsored by Shanna Babalonis, PhD, which has 6 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07668635's enrollment target sits among peer trials

30 1332nd of 2000 higher than 561 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07668635, the US trial registry maintained by the National Library of Medicine. NCT07668635 (small enrollment · none site footprint · not yet recruiting) retrieved and formatted by PlainTrial, see methodology.