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NCT07661992 · ClinicalTrials.gov registry record · Phase 1

Breast-milk Enema Administration to Stimulate Passage of Meconium

A Phase 1 study, sponsored by Wake Forest University Health Sciences.

Not yet
Registry status
Phase 1
Development phase
20
Enrollment target

NCT07661992: Clinical Trial Phase 1 study, sponsored by Wake Forest University Health Sciences.

NCT07661992 is a Phase 1 study that has not yet begun recruiting, run by Wake Forest University Health Sciences. The registered enrollment target is 20 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (67% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07661992, a Phase 1 study, has not yet begun recruiting, sponsored by Wake Forest University Health Sciences.

NOT YET RECRUITING
Registry status
Phase 1
Development phase
20 participants
Enrollment target

Study Summary

Lack of passage of meconium in preterm infants delays feeding advancement and may represent a risk factor for necrotizing enterocolitis (NEC) and spontaneous intestinal perforation (SIP). Usual management of meconium impaction has included glycerin suppositories and normal saline enemas. Various methods are used in routine neonatal care to promote meconium evacuation; however, there is no consensus on the agents used and the frequency of applications

Primary Outcome

Recruitment rate

Interventions

  • DRUG breast milk

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2026-07
Est. Completion 2027-01
Phase Phase 1
Wake Forest University Health Sciences

1,140 total trials

What is known before NCT07661992 opens enrollment

NCT07661992 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (67% lower).

The record links to 0 conditions, and to 1 intervention - of which breast milk is the first listed.

NCT07661992 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07661992 about?

NCT07661992 is a clinical study titled "Breast-milk Enema Administration to Stimulate Passage of Meconium". Lack of passage of meconium in preterm infants delays feeding advancement and may represent a risk factor for necrotizing enterocolitis (NEC) and spontaneous intestinal perforation (SIP). Usual management of meconium impaction has included glycerin suppositories and normal saline enemas. Various met...

What is the current status of trial NCT07661992?

This trial is currently not yet recruiting. It is a Phase 1 study. The enrollment target is 20 participants. The study started on 2026-07. Estimated completion is 2027-01.

What interventions are being tested in trial NCT07661992?

The interventions under investigation include: breast milk (DRUG).

Who is sponsoring clinical trial NCT07661992?

This trial is sponsored by Wake Forest University Health Sciences, which has 1,140 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07661992's enrollment target sits among peer trials

20 1629th of 2000 higher than 285 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07661992, the US trial registry maintained by the National Library of Medicine. NCT07661992 (small enrollment · none site footprint · not yet recruiting) retrieved and formatted by PlainTrial, see methodology.