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NCT07661446 · ClinicalTrials.gov registry record · Phase 1
Cannabis and Opioid Use Disorder, Study 2
A Phase 1 study, sponsored by University of Kentucky.
- Not yet
- Registry status
- Phase 1
- Development phase
- 100
- Enrollment target
NCT07661446: Clinical Trial Phase 1 study, sponsored by University of Kentucky.
NCT07661446 is a Phase 1 study that has not yet begun recruiting, run by University of Kentucky. The registered enrollment target is 100 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (67% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07661446, a Phase 1 study, has not yet begun recruiting, sponsored by University of Kentucky.
- NOT YET RECRUITING
- Registry status
- Phase 1
- Development phase
- 100 participants
- Enrollment target
Study Summary
This inpatient study enrolls healthy individuals who have opioid use disorder. Participants live at the University of Kentucky Hospital for approx. 6 weeks. During this time, we will examine how repeated doses of oral cannabis and acute doses of oral and inhaled cannabis 1) modify the intensity and time course of opioid withdrawal, 2) modify the effects of intranasal opioid administration and 3) impact the safety of opioid administration.
Primary Outcome
Opioid severity is a participant-rated outcome that will be measured on a visual analog scale (0-100)
Interventions
- DRUG Inhaled Cannabis
- DRUG Intranasal Opioid
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2026-07-30 |
| Est. Completion | 2030-01-30 |
| Phase | Phase 1 |
What is known before NCT07661446 opens enrollment
NCT07661446 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (67% higher).
The record links to 0 conditions, and to 2 interventions - of which Inhaled Cannabis is the first listed.
NCT07661446 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07661446 about?
NCT07661446 is a clinical study titled "Cannabis and Opioid Use Disorder, Study 2". This inpatient study enrolls healthy individuals who have opioid use disorder. Participants live at the University of Kentucky Hospital for approx. 6 weeks. During this time, we will examine how repeated doses of oral cannabis and acute doses of oral and inhaled cannabis 1) modify the intensity and ...
What is the current status of trial NCT07661446?
This trial is currently not yet recruiting. It is a Phase 1 study. The enrollment target is 100 participants. The study started on 2026-07-30. Estimated completion is 2030-01-30.
What interventions are being tested in trial NCT07661446?
The interventions under investigation include: Inhaled Cannabis (DRUG), Intranasal Opioid (DRUG).
Who is sponsoring clinical trial NCT07661446?
This trial is sponsored by University of Kentucky, which has 54 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07661446's enrollment target sits among peer trials
100 546th of 2000 higher than 1,411 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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