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NCT07661108 · ClinicalTrials.gov registry record · Phase 1

A Clinical Study of MK-8527 in Healthy Participants (MK-8527-021)

A Phase 1 study, sponsored by Merck Sharp & Dohme.

Recruiting
Registry status
Phase 1
Development phase
44
Enrollment target

NCT07661108 is a Phase 1 study that is actively recruiting participants, run by Merck Sharp & Dohme. The registered enrollment target is 44 participants.

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The verdict

NCT07661108, a Phase 1 study, is actively recruiting participants, sponsored by Merck Sharp & Dohme.

RECRUITING
Registry status
Phase 1
Development phase
44 participants
Enrollment target

Study Summary

Researchers are studying a medicine called MK-8527 to learn how it behaves in the body of healthy adults. The goal of this study is to learn about the effect of MK-8527 when it is taken with food or with other medicines. Researchers also want to learn about the safety of MK-8527 and if people tolerate it. Tolerate means participants will receive treatment in the trial unless they need to stop it due to health problems.

Interventions

  • DRUG Itraconazole
  • DRUG Probenecid
  • DRUG MK-8527

Trial Details

FieldValue
Enrollment Target 44 participants
Start Date 2026-06-30
Est. Completion 2026-10-09
Phase Phase 1

Sponsor

Merck Sharp & Dohme

558 total trials

What the Registry Record Tells You About NCT07661108

The ClinicalTrials.gov registry entry for NCT07661108 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 44 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Merck Sharp & Dohme, which has 558 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Itraconazole is the first listed.

NCT07661108 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT07661108 about?

NCT07661108 is a clinical study titled "A Clinical Study of MK-8527 in Healthy Participants (MK-8527-021)". Researchers are studying a medicine called MK-8527 to learn how it behaves in the body of healthy adults. The goal of this study is to learn about the effect of MK-8527 when it is taken with food or with other medicines. Researchers also want to learn about the safety of MK-8527 and if people toler...

What is the current status of trial NCT07661108?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 44 participants. The study started on 2026-06-30. Estimated completion is 2026-10-09.

What interventions are being tested in trial NCT07661108?

The interventions under investigation include: Itraconazole (DRUG), Probenecid (DRUG), MK-8527 (DRUG).

Who is sponsoring clinical trial NCT07661108?

This trial is sponsored by Merck Sharp & Dohme, which has 558 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.