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NCT07659678 · ClinicalTrials.gov registry record · Phase 2

CCR2 PET Imaging Head and Neck Squamous Cell Carcinoma

A Phase 2 study, sponsored by Washington University School of Medicine.

Not yet
Registry status
Phase 2
Development phase
90
Enrollment target

NCT07659678: Clinical Trial Phase 2 study, sponsored by Washington University School of Medicine.

NCT07659678 is a Phase 2 study that has not yet begun recruiting, run by Washington University School of Medicine. The registered enrollment target is 90 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (32% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07659678, a Phase 2 study, has not yet begun recruiting, sponsored by Washington University School of Medicine.

NOT YET RECRUITING
Registry status
Phase 2
Development phase
90 participants
Enrollment target

Study Summary

This is a prospective study to evaluate the sensitivity and specificity of Cu-64 DOTA-ECL1i PET/CT imaging to serve as a novel precision imaging tool for patients with head and neck squamous cell carcinoma (HNSCC).

Primary Outcome

64Cu-DOTA-ECL1i PET uptake will be assessed using standardized update value maximum (SUVmax). SUV is a decay-corrected measurement of activity per volume of tissue (µCi/mL) divided by the average activity per unit mass in the entire body and/or tumor-to-normal-tissue-ratio. SUVmax is the highest measured uptake of a tracer of a lesion on a PET scan.

Interventions

  • DRUG 64Cu-DOTA-ECL1i

Trial Details

FieldValue
Enrollment Target 90 participants
Start Date 2026-08-31
Est. Completion 2032-03-31
Phase Phase 2

What is known before NCT07659678 opens enrollment

NCT07659678 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 90 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (32% lower).

The record links to 0 conditions, and to 1 intervention - of which 64Cu-DOTA-ECL1i is the first listed.

NCT07659678 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07659678 about?

NCT07659678 is a clinical study titled "CCR2 PET Imaging Head and Neck Squamous Cell Carcinoma". This is a prospective study to evaluate the sensitivity and specificity of Cu-64 DOTA-ECL1i PET/CT imaging to serve as a novel precision imaging tool for patients with head and neck squamous cell carcinoma (HNSCC).

What is the current status of trial NCT07659678?

This trial is currently not yet recruiting. It is a Phase 2 study. The enrollment target is 90 participants. The study started on 2026-08-31. Estimated completion is 2032-03-31.

What interventions are being tested in trial NCT07659678?

The interventions under investigation include: 64Cu-DOTA-ECL1i (DRUG).

Who is sponsoring clinical trial NCT07659678?

This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07659678's enrollment target sits among peer trials

90 772nd of 2000 higher than 1,199 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07659678, the US trial registry maintained by the National Library of Medicine. NCT07659678 (small enrollment · none site footprint · not yet recruiting) retrieved and formatted by PlainTrial, see methodology.