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NCT07657182 · ClinicalTrials.gov registry record · Phase 4
A Prospective, Randomized, Assessor-Blinded, Multicenter Study Comparing Avance Nerve Graft and Autograft for Functional Recovery Following Mixed and Motor Peripheral Nerve Reconstruction
A Phase 4 study, sponsored by Axogen Corporation.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 178
- Enrollment target
NCT07657182: Recruiting Phase 4 study, sponsored by Axogen Corporation.
NCT07657182 is a Phase 4 study that is actively recruiting participants, run by Axogen Corporation. The registered enrollment target is 178 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (66% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07657182, a Phase 4 study, is actively recruiting participants, sponsored by Axogen Corporation.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 178 participants
- Enrollment target
Study Summary
This is a multicenter, 1:1 randomized, prospective, comparative study in participants requiring reconstruction of a mixed or motor nerve in the upper extremity. This study will consist of a screening visit, an operative visit, and 9 post-operative follow-up visits at Week 4, and Months 3, 6, 9, 12, 15, 18, 21, and 24.
Primary Outcome
Medical Research Council Classification (MRCC) of motor recovery score. This is an ordinal scale from M0-M5, with grade M0 meaning no contraction and M5 meaning full recovery in all muscles.
Interventions
- BIOLOGICAL Avance Nerve Graft
- PROCEDURE Sural nerve autograft
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 178 participants |
| Start Date | 2026-06-12 |
| Est. Completion | 2030-12-05 |
| Phase | Phase 4 |
What NCT07657182 shows while recruiting
NCT07657182 is an interventional study that assigns participants to a tested intervention. The registered 178 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (66% lower).
The record links to 0 conditions, and to 2 interventions - of which Avance Nerve Graft is the first listed.
NCT07657182 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07657182 about?
NCT07657182 is a clinical study titled "A Prospective, Randomized, Assessor-Blinded, Multicenter Study Comparing Avance Nerve Graft and Autograft for Functional Recovery Following Mixed and Motor Peripheral Nerve Reconstruction". This is a multicenter, 1:1 randomized, prospective, comparative study in participants requiring reconstruction of a mixed or motor nerve in the upper extremity. This study will consist of a screening visit, an operative visit, and 9 post-operative follow-up visits at Week 4, and Months 3, 6, 9, 12, ...
What is the current status of trial NCT07657182?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 178 participants. The study started on 2026-06-12. Estimated completion is 2030-12-05.
What interventions are being tested in trial NCT07657182?
The interventions under investigation include: Avance Nerve Graft (BIOLOGICAL), Sural nerve autograft (PROCEDURE).
Who is sponsoring clinical trial NCT07657182?
This trial is sponsored by Axogen Corporation, which has 10 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07657182's enrollment target sits among peer trials
178 477th of 2000 higher than 1,524 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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