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NCT07652580 · ClinicalTrials.gov registry record
Toxin Exposure and Immune Dysregulation in Non-Hodgkin Lymphoma
A clinical trial, sponsored by Henry M. Jackson Foundation for the Advancement of Military Medicine.
- Recruiting
- Registry status
- 300
- Enrollment target
NCT07652580: Recruiting study, sponsored by Henry M. Jackson Foundation for the Advancement of Military Medicine.
NCT07652580 is a clinical trial that is actively recruiting participants, run by Henry M. Jackson Foundation for the Advancement of Military Medicine. The registered enrollment target is 300 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07652580 is actively recruiting participants, sponsored by Henry M. Jackson Foundation for the Advancement of Military Medicine.
- RECRUITING
- Registry status
- 300 participants
- Enrollment target
Study Summary
The goal of this observational cohort study is to learn how toxin and occupational exposures, germline genetic variation, and immune dysregulation relate to B-cell non-Hodgkin lymphoma among active-duty service members and other Military Health System beneficiaries. The main questions are whether specific exposures and germline variants are associated with B-cell NHL subtype, immune dysfunction, and clinical outcomes. Participants will complete exposure and medical-history surveys, provide biospecimens for immune and genomic testing, and may be followed annually for up to 3 years.
Primary Outcome
1. Characterize and determine the prevalence of various toxin and occupational exposures in ADSMs and other MHS beneficiaries with B-cell NHL (Cohorts 1-3). 2. Characterize the B-cell NHL subtypes and health outcomes of NHL in ADSMs and other MHS beneficiaries (Cohorts 1-3). 3. Characterize immune dysregulation in ADSMs and other MHS beneficiaries with B-cell NHL. Immune dysregulation could be characterized by humoral vs cellular defects as well as innate vs adaptive defects among others (Cohort
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 300 participants |
| Start Date | 2025-05-01 |
| Est. Completion | 2028-05-01 |
What NCT07652580 shows while recruiting
NCT07652580 is an observational study that tracks outcomes without assigning an intervention. The registered 300 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 0 interventions.
NCT07652580 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07652580 about?
NCT07652580 is a clinical study titled "Toxin Exposure and Immune Dysregulation in Non-Hodgkin Lymphoma". The goal of this observational cohort study is to learn how toxin and occupational exposures, germline genetic variation, and immune dysregulation relate to B-cell non-Hodgkin lymphoma among active-duty service members and other Military Health System beneficiaries. The main questions are whether sp...
What is the current status of trial NCT07652580?
This trial is currently recruiting. The enrollment target is 300 participants. The study started on 2025-05-01. Estimated completion is 2028-05-01.
Who is sponsoring clinical trial NCT07652580?
This trial is sponsored by Henry M. Jackson Foundation for the Advancement of Military Medicine, which has 60 total clinical trials registered on ClinicalTrials.gov.
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