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NCT07652437 · ClinicalTrials.gov registry record · NA
Study of Wearable Interventions for Improving Mobility of Individuals With Knee Osteoarthritis
A NA study, sponsored by Massachusetts Institute of Technology.
- Recruiting
- Registry status
- NA
- Development phase
- 9
- Enrollment target
NCT07652437: Recruiting NA study, sponsored by Massachusetts Institute of Technology.
NCT07652437 is a NA study that is actively recruiting participants, run by Massachusetts Institute of Technology. The registered enrollment target is 9 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07652437, a NA study, is actively recruiting participants, sponsored by Massachusetts Institute of Technology.
- RECRUITING
- Registry status
- NA
- Development phase
- 9 participants
- Enrollment target
Study Summary
Knee osteoarthritis (OA) affects an estimated 654 million people over age 40 world-wide. In the United States, approximately 16% of adults over the age of 40 have knee OA. Pain, activity limitations and disability are common symptoms. Exercise is widely recommended as a non-invasive, first line strategy for people with knee OA. Yet, less than 1/3 of adults with knee OA meet recommended levels of physical activity, and rates are even lower among people who are overweight. Furthermore, adherence to evidence-based structured programs is poor once the therapeutic support is removed. End stage disease is treated by total joint replacement. Under-active people with knee OA would benefit from general walking activity, even if joint replacement surgery is expected; however, walking is difficult and motivation is low. Thus, people with knee OA encounter a difficult paradox: exercise could help decrease pain and improve function but doing so can be difficult and may not always be possible. There is a tremendous need to address this situation. This is a small device-feasibility study evaluating the Dephy ExoBoot, a wearable powered exoskeleton, in individuals with knee OA. The study assesses whether the device can reliably deliver positive assistance during walking and is tolerated across walking tasks. Additional measures, including changes in knee loading and walking speed with versus without the device, are also collected.
Primary Outcome
Number of participants that complete the walking protocol with device providing assistance without device-related restrictions.
Interventions
- DEVICE Dephy Exoboot
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 9 participants |
| Start Date | 2025-12-15 |
| Est. Completion | 2029-07-01 |
| Phase | NA |
What NCT07652437 shows while recruiting
NCT07652437 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 9 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 1 intervention - of which Dephy Exoboot is the first listed.
NCT07652437 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07652437 about?
NCT07652437 is a clinical study titled "Study of Wearable Interventions for Improving Mobility of Individuals With Knee Osteoarthritis". Knee osteoarthritis (OA) affects an estimated 654 million people over age 40 world-wide. In the United States, approximately 16% of adults over the age of 40 have knee OA. Pain, activity limitations and disability are common symptoms. Exercise is widely recommended as a non-invasive, first line stra...
What is the current status of trial NCT07652437?
This trial is currently recruiting. It is a NA study. The enrollment target is 9 participants. The study started on 2025-12-15. Estimated completion is 2029-07-01.
What interventions are being tested in trial NCT07652437?
The interventions under investigation include: Dephy Exoboot (DEVICE).
Who is sponsoring clinical trial NCT07652437?
This trial is sponsored by Massachusetts Institute of Technology, which has 24 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07652437's enrollment target sits among peer trials
9 1975th of 2000 higher than 25 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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