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NCT07652333 · ClinicalTrials.gov registry record · NA
The Effects of Strength Training on Muscle Mass and Mental Health in Adults Taking Obesity Medication
A NA study, sponsored by University of Pittsburgh.
- Recruiting
- Registry status
- NA
- Development phase
- 40
- Enrollment target
NCT07652333: Recruiting NA study, sponsored by University of Pittsburgh.
NCT07652333 is a NA study that is actively recruiting participants, run by University of Pittsburgh. The registered enrollment target is 40 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07652333, a NA study, is actively recruiting participants, sponsored by University of Pittsburgh.
- RECRUITING
- Registry status
- NA
- Development phase
- 40 participants
- Enrollment target
Study Summary
The purpose of this study is to examine the effects of resistance exercise, such as weightlifting, on retention of muscle mass and mental health in individuals taking GLP-1 RAs (an obesity medication). Resistance exercise is focused on increasing the strength of participants' muscles, such as how much participant can lift. •The duration of this study is 3 months. This includes: * Orientation session to explain study protocol, exercise program, and complete questionnaire about participants' medical history and lifestyle. * Two health assessments at baseline and at 3 months. These assessments include body composition, resting blood pressure, cardiovascular function, and muscular strength. Both the resistance exercise group and the control group will complete assessments at baseline and again at 3 months. After the 3-month period, individuals in the control group may choose to participate in the exercise training and complete the optional 6-month assessments. * Personalized resistance exercise sessions for 60 minutes per session, twice per week, for 3 months.
Primary Outcome
Dual-energy X-ray absorptiometry (DEXA) will be used to assess fat mass and lean mass. Body fat will be expressed as a percentage of total body composition, and lean mass will be expressed as a percentage of total body composition. Change in each variable will be calculated as the Week 12 value minus the baseline value. Positive values indicate an increase in body fat or lean mass, and negative values indicate a decrease.
Interventions
- BEHAVIORAL Resistance Exercise
- DRUG GLP-1 RAs
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2026-05-25 |
| Est. Completion | 2027-05-31 |
| Phase | NA |
What NCT07652333 shows while recruiting
NCT07652333 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).
The record links to 0 conditions, and to 2 interventions - of which Resistance Exercise is the first listed.
NCT07652333 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07652333 about?
NCT07652333 is a clinical study titled "The Effects of Strength Training on Muscle Mass and Mental Health in Adults Taking Obesity Medication". The purpose of this study is to examine the effects of resistance exercise, such as weightlifting, on retention of muscle mass and mental health in individuals taking GLP-1 RAs (an obesity medication). Resistance exercise is focused on increasing the strength of participants' muscles, such as how mu...
What is the current status of trial NCT07652333?
This trial is currently recruiting. It is a NA study. The enrollment target is 40 participants. The study started on 2026-05-25. Estimated completion is 2027-05-31.
What interventions are being tested in trial NCT07652333?
The interventions under investigation include: Resistance Exercise (BEHAVIORAL), GLP-1 RAs (DRUG).
Who is sponsoring clinical trial NCT07652333?
This trial is sponsored by University of Pittsburgh, which has 1,238 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07652333's enrollment target sits among peer trials
40 1447th of 2000 higher than 465 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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