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NCT07651787 · ClinicalTrials.gov registry record · NA
Using Light Therapy for Mild Cognitive Impairment
A NA study, sponsored by University of Oklahoma.
- Recruiting
- Registry status
- NA
- Development phase
- 40
- Enrollment target
NCT07651787 is a NA study that is actively recruiting participants, run by University of Oklahoma. The registered enrollment target is 40 participants.
The verdict
NCT07651787, a NA study, is actively recruiting participants, sponsored by University of Oklahoma.
- RECRUITING
- Registry status
- NA
- Development phase
- 40 participants
- Enrollment target
Study Summary
The goal of this clinical trial is to test whether transcranial photobiomodulation (tPBM), a non-invasive brain stimulation technique using near-infrared light, can improve brain blood flow regulation (neurovascular coupling) and cognitive function in people with mild cognitive impairment (MCI). The main questions it aims to answer are: * Does tPBM enhance cognitive function and cerebral hemodynamic responses during memory and finger tapping tasks? * Does tPBM reduce oxidative stress, inflammation, and mitigate brain cell damage? * Is cognitive improvement linked to amyloid status, greater cerebral hemodynamic response, and lower levels of brain inflammation and oxidative stress? Researchers will compare an active tPBM treatment arm to a sham treatment arm to see if tPBM leads to measurable improvements in brain activity and cognitive function compared to no active stimulation. Participants will: * Receive a 20-minute-long active tPBM or sham stimulation session once per day, 6 times per week, for 12 weeks. * Complete questionnaires and an iPad-based cognitive testing protocol. * Complete memory and motor tasks while their brain activity is measured using non-invasive techniques: simultaneous functional near-infrared spectroscopy (fNIRS) and electroencephalography (EEG). Dynamic analysis of the vessels in the eye will also be performed based on eligibility. Transcranial Doppler (TCD) flowmetry is optionally performed. * Provide blood samples to test for biomarkers of inflammation, oxidative stress, and brain cell damage.
Interventions
- DEVICE Active Vielight Neuro RX-Duo device -Active transcranial photobiomodulation
- DEVICE Sham Vielight Neuro RX-Duo device -Sham transcranial photobiomodulation
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2025-10-01 |
| Est. Completion | 2026-12-31 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07651787
The ClinicalTrials.gov registry entry for NCT07651787 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Oklahoma, which has 358 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Active Vielight Neuro RX-Duo device -Active transcranial photobiomodulation is the first listed.
NCT07651787 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT07651787 about?
NCT07651787 is a clinical study titled "Using Light Therapy for Mild Cognitive Impairment". The goal of this clinical trial is to test whether transcranial photobiomodulation (tPBM), a non-invasive brain stimulation technique using near-infrared light, can improve brain blood flow regulation (neurovascular coupling) and cognitive function in people with mild cognitive impairment (MCI). The...
What is the current status of trial NCT07651787?
This trial is currently recruiting. It is a NA study. The enrollment target is 40 participants. The study started on 2025-10-01. Estimated completion is 2026-12-31.
What interventions are being tested in trial NCT07651787?
The interventions under investigation include: Active Vielight Neuro RX-Duo device -Active transcranial photobiomodulation (DEVICE), Sham Vielight Neuro RX-Duo device -Sham transcranial photobiomodulation (DEVICE).
Who is sponsoring clinical trial NCT07651787?
This trial is sponsored by University of Oklahoma, which has 358 total clinical trials registered on ClinicalTrials.gov.
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