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NCT07644923 · ClinicalTrials.gov registry record · Phase 4
Postoperative Non-Opioid Pain Management Utilizing Local Anesthetics Coupled With Modulated Coagulation
A Phase 4 study, sponsored by NYU Langone Health.
- Not yet
- Registry status
- Phase 4
- Development phase
- 40
- Enrollment target
NCT07644923: Clinical Trial Phase 4 study, sponsored by NYU Langone Health.
NCT07644923 is a Phase 4 study that has not yet begun recruiting, run by NYU Langone Health. The registered enrollment target is 40 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (92% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07644923, a Phase 4 study, has not yet begun recruiting, sponsored by NYU Langone Health.
- NOT YET RECRUITING
- Registry status
- Phase 4
- Development phase
- 40 participants
- Enrollment target
Study Summary
This study is a prospective randomized trial examining the effect of tranexamic acid (TXA) and aminocaproic acid (ε-Ahx) with local anesthetics and thrombin in all electively created surgical wound beds in hand surgery to provide long term pain relief and decrease the use of postoperative narcotics. All surgical created wounds for any hand surgery will be treated in a randomized fashion with the following four arms: 1. Bupivacaine + lidocaine 2. Bupivacaine + lidocaine + thrombin 3. Bupivacaine + lidocaine + thrombin + tranexamic acid 4. Bupivacaine + lidocaine + thrombin + aminocaproic acid All are applied topically to surgical bed prior to closure of skin.
Primary Outcome
Pain rated on a scale from 0 (no pain) to 10 (highest level of pain ever experienced).
Interventions
- DRUG Bupivacaine
- DRUG Lidocaine
- DRUG Tranexamic acid
- DRUG Aminocaproic acid
- DRUG Thrombin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2026-08-01 |
| Est. Completion | 2029-02-01 |
| Phase | Phase 4 |
What is known before NCT07644923 opens enrollment
NCT07644923 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (92% lower).
The record links to 0 conditions, and to 5 interventions - of which Bupivacaine is the first listed.
NCT07644923 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07644923 about?
NCT07644923 is a clinical study titled "Postoperative Non-Opioid Pain Management Utilizing Local Anesthetics Coupled With Modulated Coagulation". This study is a prospective randomized trial examining the effect of tranexamic acid (TXA) and aminocaproic acid (ε-Ahx) with local anesthetics and thrombin in all electively created surgical wound beds in hand surgery to provide long term pain relief and decrease the use of postoperative narcotics....
What is the current status of trial NCT07644923?
This trial is currently not yet recruiting. It is a Phase 4 study. The enrollment target is 40 participants. The study started on 2026-08-01. Estimated completion is 2029-02-01.
What interventions are being tested in trial NCT07644923?
The interventions under investigation include: Bupivacaine (DRUG), Lidocaine (DRUG), Tranexamic acid (DRUG), Aminocaproic acid (DRUG), Thrombin (DRUG).
Who is sponsoring clinical trial NCT07644923?
This trial is sponsored by NYU Langone Health, which has 1,164 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07644923's enrollment target sits among peer trials
40 1397th of 2000 higher than 533 of 2,000 other Phase 4 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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