Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT07639021 · ClinicalTrials.gov registry record · Phase 2

A Research Study Comparing Different Ways of Increasing the Dose of NNC0662-0419 in Participants With Obesity

A Phase 2 study, sponsored by Novo Nordisk A/S.

Recruiting
Registry status
Phase 2
Development phase
230
Enrollment target

NCT07639021: Recruiting Phase 2 study, sponsored by Novo Nordisk A/S.

NCT07639021 is a Phase 2 study that is actively recruiting participants, run by Novo Nordisk A/S. The registered enrollment target is 230 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (73% higher). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT07639021, a Phase 2 study, is actively recruiting participants, sponsored by Novo Nordisk A/S.

RECRUITING
Registry status
Phase 2
Development phase
230 participants
Enrollment target

Study Summary

The purpose of the study is to find out if NNC0662-0419 is safe and effective for treating participants living with obesity.

Primary Outcome

Measured as number of events.

Interventions

  • DRUG Semaglutide
  • DRUG NNC0662-0419
  • DRUG NNC0662-0419 Placebo
  • DRUG Semaglutide placebo

Trial Details

FieldValue
Enrollment Target 230 participants
Start Date 2026-06-09
Est. Completion 2027-07-12
Phase Phase 2
Novo Nordisk A/S

431 total trials

What NCT07639021 shows while recruiting

NCT07639021 is an interventional study that assigns participants to a tested intervention. The registered 230 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (73% higher).

The record links to 0 conditions, and to 4 interventions - of which Semaglutide is the first listed.

NCT07639021 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07639021 about?

NCT07639021 is a clinical study titled "A Research Study Comparing Different Ways of Increasing the Dose of NNC0662-0419 in Participants With Obesity". The purpose of the study is to find out if NNC0662-0419 is safe and effective for treating participants living with obesity.

What is the current status of trial NCT07639021?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 230 participants. The study started on 2026-06-09. Estimated completion is 2027-07-12.

What interventions are being tested in trial NCT07639021?

The interventions under investigation include: Semaglutide (DRUG), NNC0662-0419 (DRUG), NNC0662-0419 Placebo (DRUG), Semaglutide placebo (DRUG).

Who is sponsoring clinical trial NCT07639021?

This trial is sponsored by Novo Nordisk A/S, which has 431 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07639021's enrollment target sits among peer trials

230 257th of 2000 higher than 1,737 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT02710253 · 230 participants · Phase 2

    Salvage Radiation Therapy in Treating Patients With Metastatic Cancer That Has Progressed After Systemic Immunotherapy

  • NCT02777879 · 230 participants

    Lung Microbiome and Inflammation in Early COPD

  • NCT03824483 · 230 participants · Phase 2

    Study of Zanubrutinib, Obinutuzumab, and Venetoclax in Patients With Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL)

  • NCT03833622 · 230 participants · NA

    Shared Decision Making to Improve Goals of Care in the ED

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT07639021, the US trial registry maintained by the National Library of Medicine. NCT07639021 (mid enrollment · none site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.