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NCT07634627 · ClinicalTrials.gov registry record
UNderstanding the Causes Of Idiopathic Scoliosis Through the Longitudinal Analysis of Proteomic Markers: the UNCOIL Study
A clinical trial, sponsored by University of Colorado, Denver.
- Recruiting
- Registry status
- 500
- Enrollment target
NCT07634627: Recruiting study, sponsored by University of Colorado, Denver.
NCT07634627 is a clinical trial that is actively recruiting participants, run by University of Colorado, Denver. The registered enrollment target is 500 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07634627 is actively recruiting participants, sponsored by University of Colorado, Denver.
- RECRUITING
- Registry status
- 500 participants
- Enrollment target
Study Summary
The goal of this observational study is to find clinical, demographic, and protein biomarkers that scoliosis progression (scoliosis curve increases) and/or differ between participants with scoliosis versus those without scoliosis. The investigators aim to answer the following questions: 1. Are age, sex, skeletal maturity, and family history associated with scoliosis curve progression? 2. Do protein levels differ between progressive and non-progressive cases? 3. Do protein levels change between baseline and follow-up visits in progressive and non-progressive scoliosis cases? 4. Do proteins differ between participants with AIS vs those without AIS? 5. Do proteins or change in proteins differ between participants with AIS vs those with scoliosis secondary to neuromuscular conditions. Participants will: * Participate in two research visits 6-12 months apart at a Children's Hospital Colorado location. * Participate in a blood draw at each study visit to collect about 3 tablespoons of blood. * Fill out surveys yearly regarding new medical visits, pain, physical function, anxiety and depression, medical and family history, and current medications.
Primary Outcome
The change in Cobb angle of the primary scoliosis curve between the baseline and the 6-12 month visit will be quantified.
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 500 participants |
| Start Date | 2024-12-05 |
| Est. Completion | 2031-12 |
What NCT07634627 shows while recruiting
NCT07634627 is an observational study that tracks outcomes without assigning an intervention. The registered 500 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 0 interventions.
NCT07634627 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07634627 about?
NCT07634627 is a clinical study titled "UNderstanding the Causes Of Idiopathic Scoliosis Through the Longitudinal Analysis of Proteomic Markers: the UNCOIL Study". The goal of this observational study is to find clinical, demographic, and protein biomarkers that scoliosis progression (scoliosis curve increases) and/or differ between participants with scoliosis versus those without scoliosis. The investigators aim to answer the following questions: 1. Are age,...
What is the current status of trial NCT07634627?
This trial is currently recruiting. The enrollment target is 500 participants. The study started on 2024-12-05. Estimated completion is 2031-12.
Who is sponsoring clinical trial NCT07634627?
This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.
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