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NCT07630207 · ClinicalTrials.gov registry record
Vascular Function in Adults With Down Syndrome
A clinical trial, sponsored by University of Nevada, Las Vegas.
- Recruiting
- Registry status
- 24
- Enrollment target
NCT07630207: Recruiting study, sponsored by University of Nevada, Las Vegas.
NCT07630207 is a clinical trial that is actively recruiting participants, run by University of Nevada, Las Vegas. The registered enrollment target is 24 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07630207 is actively recruiting participants, sponsored by University of Nevada, Las Vegas.
- RECRUITING
- Registry status
- 24 participants
- Enrollment target
Study Summary
Adults with Down syndrome (Ds) are often thought to have a lower risk of heart and blood vessel disease because they tend to have lower blood pressure and fewer heart attacks than people without Ds. However, recent research suggests that heart and blood vessel diseases, including stroke, are becoming a more common cause of death in adults with Ds as life expectancy increases. Despite these findings, studies examining heart and blood vessel health in adults with Ds have produced mixed results, making it difficult to determine their true risk and whether preventive strategies are needed. This study will investigate the health of blood vessels in adults with Ds and compare the results with those of adults without Ds. Healthy blood vessels are important because they help deliver blood and oxygen throughout the body. Changes in blood vessel function and stiffness can occur with aging and may increase the risk of heart disease, stroke, kidney disease, and memory problems. The study aims to determine whether adults with Ds experience changes in blood vessel health that may place them at increased cardiovascular risk. Specifically, the study will: (1) Examine how well blood vessels function in adults with Ds; (2) Measure the stiffness of arteries in adults with Ds; (3) Compare two methods used to assess blood vessel function to determine whether a simpler exercise-based test provides results similar to a commonly used standard test. The findings may improve understanding of cardiovascular risk in adults with Ds and help guide future strategies to promote healthy aging in this population.
Primary Outcome
PWV (m/s) will be measured using small, non-invasive pressure-sensitive transducers that record distension waveforms over superficial arteries like the carotid and femoral artery (PulsePen® DiaTecne - Italia).
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2026-04-09 |
| Est. Completion | 2026-12-31 |
What NCT07630207 shows while recruiting
NCT07630207 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 24 participants, a relatively small participant target.
The record links to 0 conditions, and to 0 interventions.
NCT07630207 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07630207 about?
NCT07630207 is a clinical study titled "Vascular Function in Adults With Down Syndrome". Adults with Down syndrome (Ds) are often thought to have a lower risk of heart and blood vessel disease because they tend to have lower blood pressure and fewer heart attacks than people without Ds. However, recent research suggests that heart and blood vessel diseases, including stroke, are becomin...
What is the current status of trial NCT07630207?
This trial is currently recruiting. The enrollment target is 24 participants. The study started on 2026-04-09. Estimated completion is 2026-12-31.
Who is sponsoring clinical trial NCT07630207?
This trial is sponsored by University of Nevada, Las Vegas, which has 52 total clinical trials registered on ClinicalTrials.gov.
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