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NCT07623785 · ClinicalTrials.gov registry record · NA

Assessing the Influence of Habitual Beef Intake on Key Molecular Markers of Brain Health

A NA study, sponsored by South Dakota State University.

Recruiting
Registry status
NA
Development phase
20
Enrollment target

NCT07623785: Recruiting NA study, sponsored by South Dakota State University.

NCT07623785 is a NA study that is actively recruiting participants, run by South Dakota State University. The registered enrollment target is 20 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07623785, a NA study, is actively recruiting participants, sponsored by South Dakota State University.

RECRUITING
Registry status
NA
Development phase
20 participants
Enrollment target

Study Summary

his study investigates whether eating lean beef every day can help support brain health and healthy aging in older adults. As people age, protecting memory and cognitive function becomes increasingly important. Lean beef is a rich source of essential nutrients-such as vitamin B12, iron, zinc, and creatine-that are known to support brain function. However, the direct biological effects of a beef-rich diet on brain health markers are not fully understood. In this study, researchers will recruit 20 generally healthy older adults (aged 65 and older) to participate in a dietary feeding trial. Participants will complete two separate 2-week dietary phases. During one phase, participants will consume 5.5 ounces (156 grams) of provided lean beef daily. During the other phase, they will consume an iso-caloric, protein-matched, non-beef control food daily. A two-week "washout" period, where participants return to their normal diets, will separate the two phases to ensure there are no overlapping effects. Researchers will collect blood, urine, stool, and saliva samples at the beginning and end of each 2-week dietary phase. These samples will be analyzed to see if the lean beef diet improves specific biological markers in the blood related to memory, nerve protection, and overall brain aging. Ultimately, the findings from this study will help determine if incorporating lean beef into a regular diet can be a natural, food-based strategy to help preserve neurological health in older adults.

Primary Outcome

Quantitative change in fasting plasma concentrations of p-tau217, a blood-based biomarker indicative of neurodegeneration and cognitive decline. This will be measured using commercially available Enzyme-Linked Immunosorbent Assays

Interventions

  • OTHER Lean Beef
  • OTHER Non-Beef Control

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2026-06-03
Est. Completion 2027-07-31
Phase NA
South Dakota State University

11 total trials

What NCT07623785 shows while recruiting

NCT07623785 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).

The record links to 0 conditions, and to 2 interventions - of which Lean Beef is the first listed.

NCT07623785 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07623785 about?

NCT07623785 is a clinical study titled "Assessing the Influence of Habitual Beef Intake on Key Molecular Markers of Brain Health". his study investigates whether eating lean beef every day can help support brain health and healthy aging in older adults. As people age, protecting memory and cognitive function becomes increasingly important. Lean beef is a rich source of essential nutrients-such as vitamin B12, iron, zinc, and cr...

What is the current status of trial NCT07623785?

This trial is currently recruiting. It is a NA study. The enrollment target is 20 participants. The study started on 2026-06-03. Estimated completion is 2027-07-31.

What interventions are being tested in trial NCT07623785?

The interventions under investigation include: Lean Beef (OTHER), Non-Beef Control (OTHER).

Who is sponsoring clinical trial NCT07623785?

This trial is sponsored by South Dakota State University, which has 11 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07623785's enrollment target sits among peer trials

20 1768th of 2000 higher than 140 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07623785, the US trial registry maintained by the National Library of Medicine. NCT07623785 (small enrollment · none site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.