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NCT07612293 · ClinicalTrials.gov registry record · NA
STAGE-MTC Trial Thyroid Lobectomy With Ipsilateral Central Neck Dissection
A NA study, sponsored by Jonsson Comprehensive Cancer Center.
- Not yet
- Registry status
- NA
- Development phase
- 100
- Enrollment target
NCT07612293 is a NA study that has not yet begun recruiting, run by Jonsson Comprehensive Cancer Center. The registered enrollment target is 100 participants.
The verdict
NCT07612293, a NA study, has not yet begun recruiting, sponsored by Jonsson Comprehensive Cancer Center.
- NOT YET RECRUITING
- Registry status
- NA
- Development phase
- 100 participants
- Enrollment target
Study Summary
This clinical trial studies how well thyroid lobectomy with ipsilateral central neck dissection works to treat medullary thyroid cancer (MTC) in patients without a germline RET mutation (sporadic). Currently, sporadic and germline RET (rearranged during transfection) mutation positive MTCs that are limited to the thyroid are managed in the same way, complete surgical removal of the entire thyroid gland (total thyroidectomy) with surgical removal of lymph nodes and other tissues on both sides of the neck (bilateral central neck dissection). Total thyroidectomy and bilateral central neck dissection carry a high risk of complications, and total thyroidectomy requires patients to take lifelong thyroid hormone replacement therapy, which can impact quality of life. Research has shown that patients with sporadic MTC do not have a high risk of developing MTC in the remaining normal thyroid tissue and that they may be able to be managed differently than patients with germline RET mutations. Thyroid lobectomy with ipsilateral central neck dissection is a surgical procedure which removes only the lobe of the thyroid gland that is affected by cancer as well as the lymph nodes and other tissues from the affected side of the neck. Thyroid lobectomy with ipsilateral central neck dissection may be a safer, more tolerable, and/or more effective way to treat sporadic MTC.
Interventions
- PROCEDURE Biospecimen Collection
- PROCEDURE Neck Dissection
- PROCEDURE FDG-Positron Emission Tomography and Computed Tomography Scan
- PROCEDURE Ga-68 PET/CT Scan
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2026-09-02 |
| Est. Completion | 2032-04-21 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07612293
The ClinicalTrials.gov registry entry for NCT07612293 describes a study currently listed as not yet recruiting, categorized as NA. The registered enrollment target is 100 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Jonsson Comprehensive Cancer Center, which has 321 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 4 interventions - of which Biospecimen Collection is the first listed.
NCT07612293 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT07612293 about?
NCT07612293 is a clinical study titled "STAGE-MTC Trial Thyroid Lobectomy With Ipsilateral Central Neck Dissection". This clinical trial studies how well thyroid lobectomy with ipsilateral central neck dissection works to treat medullary thyroid cancer (MTC) in patients without a germline RET mutation (sporadic). Currently, sporadic and germline RET (rearranged during transfection) mutation positive MTCs that are ...
What is the current status of trial NCT07612293?
This trial is currently not yet recruiting. It is a NA study. The enrollment target is 100 participants. The study started on 2026-09-02. Estimated completion is 2032-04-21.
What interventions are being tested in trial NCT07612293?
The interventions under investigation include: Biospecimen Collection (PROCEDURE), Neck Dissection (PROCEDURE), FDG-Positron Emission Tomography and Computed Tomography Scan (PROCEDURE), Ga-68 PET/CT Scan (PROCEDURE).
Who is sponsoring clinical trial NCT07612293?
This trial is sponsored by Jonsson Comprehensive Cancer Center, which has 321 total clinical trials registered on ClinicalTrials.gov.
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