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NCT07611110 · ClinicalTrials.gov registry record · Phase 3
AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)
A Phase 3 study, sponsored by AstraZeneca.
- Recruiting
- Registry status
- Phase 3
- Development phase
- 670
- Enrollment target
NCT07611110: Recruiting Phase 3 study, sponsored by AstraZeneca.
NCT07611110 is a Phase 3 study that is actively recruiting participants, run by AstraZeneca. The registered enrollment target is 670 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (13% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07611110, a Phase 3 study, is actively recruiting participants, sponsored by AstraZeneca.
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 670 participants
- Enrollment target
Study Summary
The intention of the study is to demonstrate superiority of AZD2265 relative to standard of care treatments by assessment of radiographic progression-free survival (rPFS) and overall survival (OS) in participants with mCRPC.
Primary Outcome
rPFS is defined as the time from randomisation to radiographic progression, as assessed by the BICR per RECIST 1.1 (soft tissue) and/or PCWG3 criteria (bone), or death due to any cause.
Interventions
- DRUG Apalutamide
- DRUG Enzalutamide
- DRUG Abiraterone
- DRUG Cabazitaxel
- DRUG AZD2265
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 670 participants |
| Start Date | 2026-05-04 |
| Est. Completion | 2029-12-20 |
| Phase | Phase 3 |
What NCT07611110 shows while recruiting
NCT07611110 is an interventional study that assigns participants to a tested intervention. The registered 670 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (13% lower).
The record links to 0 conditions, and to 5 interventions - of which Apalutamide is the first listed.
NCT07611110 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07611110 about?
NCT07611110 is a clinical study titled "AZD2265 Compared With Standard of Care in PSMA-positive Metastatic Castration-resistant Prostate Cancer (VECTRA-01)". The intention of the study is to demonstrate superiority of AZD2265 relative to standard of care treatments by assessment of radiographic progression-free survival (rPFS) and overall survival (OS) in participants with mCRPC.
What is the current status of trial NCT07611110?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 670 participants. The study started on 2026-05-04. Estimated completion is 2029-12-20.
What interventions are being tested in trial NCT07611110?
The interventions under investigation include: Apalutamide (DRUG), Enzalutamide (DRUG), Abiraterone (DRUG), Cabazitaxel (DRUG), AZD2265 (DRUG).
Who is sponsoring clinical trial NCT07611110?
This trial is sponsored by AstraZeneca, which has 1,285 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07611110's enrollment target sits among peer trials
670 546th of 2000 higher than 1,454 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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