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NCT07609914 · ClinicalTrials.gov registry record · Phase 4

A Study to Learn About the Safety of Taking an Additional Dose of the Medicine Rimegepant in Adults With Migraine

A Phase 4 study, sponsored by Pfizer.

Recruiting
Registry status
Phase 4
Development phase
400
Enrollment target

NCT07609914: Recruiting Phase 4 study, sponsored by Pfizer.

NCT07609914 is a Phase 4 study that is actively recruiting participants, run by Pfizer. The registered enrollment target is 400 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (23% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07609914, a Phase 4 study, is actively recruiting participants, sponsored by Pfizer.

RECRUITING
Registry status
Phase 4
Development phase
400 participants
Enrollment target

Study Summary

Acute treatments for migraine may not provide sufficient pain relief after an initial dose, and a second dose of a given medication may be needed to fully abort an attack. International Headache Society (IHS) global practice recommendations for the Acute Treatment of Migraine suggest a second dose of the same medication within the recommended dose limit in people with headache relapse after successful initial treatment of a migraine attack. The primary purpose of this study is to evaluate the safety and tolerability of redosing of rimegepant when taken for the acute treatment of a migraine attack, as it is possible that some patients may benefit from a second dose of rimegepant in this setting.

Interventions

  • DRUG Rimegepant

Trial Details

FieldValue
Enrollment Target 400 participants
Start Date 2026-05-28
Est. Completion 2028-05-15
Phase Phase 4
Pfizer

1,845 total trials

What NCT07609914 shows while recruiting

NCT07609914 is an interventional study that assigns participants to a tested intervention. The registered 400 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (23% lower).

The record links to 0 conditions, and to 1 intervention - of which Rimegepant is the first listed.

NCT07609914 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07609914 about?

NCT07609914 is a clinical study titled "A Study to Learn About the Safety of Taking an Additional Dose of the Medicine Rimegepant in Adults With Migraine". Acute treatments for migraine may not provide sufficient pain relief after an initial dose, and a second dose of a given medication may be needed to fully abort an attack. International Headache Society (IHS) global practice recommendations for the Acute Treatment of Migraine suggest a second dose o...

What is the current status of trial NCT07609914?

This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 400 participants. The study started on 2026-05-28. Estimated completion is 2028-05-15.

What interventions are being tested in trial NCT07609914?

The interventions under investigation include: Rimegepant (DRUG).

Who is sponsoring clinical trial NCT07609914?

This trial is sponsored by Pfizer, which has 1,845 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07609914's enrollment target sits among peer trials

400 211th of 2000 higher than 1,784 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07609914, the US trial registry maintained by the National Library of Medicine. NCT07609914 (mid enrollment · none site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.