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NCT07607665 · ClinicalTrials.gov registry record · NA

Spinal Cord Associative Plasticity in Cerebral Palsy

A NA study, sponsored by Columbia University.

Recruiting
Registry status
NA
Development phase
25
Enrollment target

NCT07607665: Recruiting NA study, sponsored by Columbia University.

NCT07607665 is a NA study that is actively recruiting participants, run by Columbia University. The registered enrollment target is 25 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07607665, a NA study, is actively recruiting participants, sponsored by Columbia University.

RECRUITING
Registry status
NA
Development phase
25 participants
Enrollment target

Study Summary

Associative plasticity has been used to promote functional recovery from conditions affecting movement. The long term goal of this project is to use electrical stimulation techniques to improve arm and hand function. The goal of this prospective experimental study in adults with hemiplegic cerebral palsy (hCP) is to test the effects of pairing hand motor cortical and median nerve stimulation targeted to induce plasticity in the cervical spinal cord. Based on preliminary data in neurotypical adults, the investigators are testing the effects of this approach in adults with hCP. This study will first verify the present stimulation parameters as sufficient to promote induction of associative plasticity of sensorimotor connections for manual dexterity in adults with hCP. This will be assessed through neurophysiological, biomechanical, and clinical functional outcome measures. Successful pairing showing meaningful improvements in dexterity could then be used as an impetus for a larger study examining the efficacy of SCAP in people with hCP.

Primary Outcome

Size of muscle response will be measured in response to brain stimulation. This value will be normalized to the equivalent measure taken before the SCAP protocol.

Interventions

  • DEVICE Paired brain and nerve stimulation

Trial Details

FieldValue
Enrollment Target 25 participants
Start Date 2026-06
Est. Completion 2032-05
Phase NA
Columbia University

958 total trials

What NCT07607665 shows while recruiting

NCT07607665 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 25 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).

The record links to 0 conditions, and to 1 intervention - of which Paired brain and nerve stimulation is the first listed.

NCT07607665 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07607665 about?

NCT07607665 is a clinical study titled "Spinal Cord Associative Plasticity in Cerebral Palsy". Associative plasticity has been used to promote functional recovery from conditions affecting movement. The long term goal of this project is to use electrical stimulation techniques to improve arm and hand function. The goal of this prospective experimental study in adults with hemiplegic cerebral ...

What is the current status of trial NCT07607665?

This trial is currently recruiting. It is a NA study. The enrollment target is 25 participants. The study started on 2026-06. Estimated completion is 2032-05.

What interventions are being tested in trial NCT07607665?

The interventions under investigation include: Paired brain and nerve stimulation (DEVICE).

Who is sponsoring clinical trial NCT07607665?

This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07607665's enrollment target sits among peer trials

25 1712th of 2000 higher than 265 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07607665, the US trial registry maintained by the National Library of Medicine. NCT07607665 (small enrollment · none site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.