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NCT07599774 · ClinicalTrials.gov registry record · NA
Optimal Targeted High-definition Transcranial Direct Current Stimulation for Reducing Post-stroke Upper Limb Motor Impairments
A NA study, sponsored by Carle Foundation Hospital.
- Not yet
- Registry status
- NA
- Development phase
- 16
- Enrollment target
NCT07599774: Clinical Trial NA study, sponsored by Carle Foundation Hospital.
NCT07599774 is a NA study that has not yet begun recruiting, run by Carle Foundation Hospital. The registered enrollment target is 16 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07599774, a NA study, has not yet begun recruiting, sponsored by Carle Foundation Hospital.
- NOT YET RECRUITING
- Registry status
- NA
- Development phase
- 16 participants
- Enrollment target
Study Summary
Non-invasive, non-pharmaceutical technologies that augment routine clinical practice for brain diseases and manage chronic symptoms have advanced rapidly over the past two decades. Among these, non-invasive brain stimulation such as transcranial direct current stimulation (tDCS) promotes neuroplasticity in injured brains, with fewer side effects and risks than invasive, implanted approaches such as deep-brain stimulation. Stimulating the brain can improve its function and help with recovery after a stroke. It has been a challenge to do this non-invasively. This is because the brain is reshaped after a stroke, and thus, it is difficult to find the right places to stimulate from the outside. In previous research, investigators found that optimal type and target of tDCS varied among subjects. The goal of this pilot trial is to test the feasibility of combining individually optimized, targeted high-definition tDCS (THD-tDCS) with rehabilitation therapy. Investigators will include 16 chronic stroke subjects with their optimal stimulation setup, obtained from their previous research. The participants will be computer-randomized into two equal-sized groups to receive either optimal THD-tDCS or sham stimulation, together with rehabilitation therapy (modified constraint-induced movement therapy, mCIMT) for five sessions over two weeks. Outcome measures will be collected at the baseline and right after the final intervention session. The primary outcome measure will be the change in the FM-UE score from baseline to immediately post the final intervention to assess the immediate effect of the intervention on upper extremity motor impairment. The secondary outcome measure will be the Wolf Motor Function Test time score to evaluate the immediate effect on functional motor performance.
Interventions
- DEVICE High-definition transcranial direct stimulation: sham
- DEVICE High-definition transcranial direct stimulation: optimal
- BEHAVIORAL Modified constraint-induced movement therapy
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 2026-07-01 |
| Est. Completion | 2027-06-30 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07599774
The ClinicalTrials.gov registry entry for NCT07599774 describes a study currently listed as not yet recruiting, categorized as NA. The registered enrollment target is 16 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Carle Foundation Hospital, which has 3 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 3 interventions - of which High-definition transcranial direct stimulation: sham is the first listed.
NCT07599774 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT07599774 about?
NCT07599774 is a clinical study titled "Optimal Targeted High-definition Transcranial Direct Current Stimulation for Reducing Post-stroke Upper Limb Motor Impairments". Non-invasive, non-pharmaceutical technologies that augment routine clinical practice for brain diseases and manage chronic symptoms have advanced rapidly over the past two decades. Among these, non-invasive brain stimulation such as transcranial direct current stimulation (tDCS) promotes neuroplasti...
What is the current status of trial NCT07599774?
This trial is currently not yet recruiting. It is a NA study. The enrollment target is 16 participants. The study started on 2026-07-01. Estimated completion is 2027-06-30.
What interventions are being tested in trial NCT07599774?
The interventions under investigation include: High-definition transcranial direct stimulation: sham (DEVICE), High-definition transcranial direct stimulation: optimal (DEVICE), Modified constraint-induced movement therapy (BEHAVIORAL).
Who is sponsoring clinical trial NCT07599774?
This trial is sponsored by Carle Foundation Hospital, which has 3 total clinical trials registered on ClinicalTrials.gov.
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