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NCT07598734 · ClinicalTrials.gov registry record · Phase 4
Doxepin Alone or Combined With Ramelteon Versus Placebo for Improving Sleep Quality After Primary Total Knee Arthroplasty
A Phase 4 study, sponsored by University of Washington.
- Not yet
- Registry status
- Phase 4
- Development phase
- 129
- Enrollment target
NCT07598734 is a Phase 4 study that has not yet begun recruiting, run by University of Washington. The registered enrollment target is 129 participants.
The verdict
NCT07598734, a Phase 4 study, has not yet begun recruiting, sponsored by University of Washington.
- NOT YET RECRUITING
- Registry status
- Phase 4
- Development phase
- 129 participants
- Enrollment target
Study Summary
Many patients experience poor sleep during recovery after total knee arthroplasty (TKA). Disturbed sleep can last weeks to months and may worsen pain, slow healing, and reduce overall quality of life. Few safe, effective, evidence-based options exist to improve sleep during this recovery period. This study aims to determine whether the medications doxepin, either alone or in combination with ramelteon, can improve sleep quality during early recovery after TKA. The investigators will also evaluate whether improved sleep leads to better pain control, knee function, and overall quality of life.
Interventions
- DRUG Placebo Tablets
- DRUG Doxepin 6 mg
- DRUG Ramelteon 8 mg
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 129 participants |
| Start Date | 2026-06 |
| Est. Completion | 2028-06 |
| Phase | Phase 4 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07598734
The ClinicalTrials.gov registry entry for NCT07598734 describes a study currently listed as not yet recruiting, categorized as Phase 4. The registered enrollment target is 129 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Washington, which has 1,048 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 3 interventions - of which Placebo Tablets is the first listed.
NCT07598734 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT07598734 about?
NCT07598734 is a clinical study titled "Doxepin Alone or Combined With Ramelteon Versus Placebo for Improving Sleep Quality After Primary Total Knee Arthroplasty". Many patients experience poor sleep during recovery after total knee arthroplasty (TKA). Disturbed sleep can last weeks to months and may worsen pain, slow healing, and reduce overall quality of life. Few safe, effective, evidence-based options exist to improve sleep during this recovery period. Thi...
What is the current status of trial NCT07598734?
This trial is currently not yet recruiting. It is a Phase 4 study. The enrollment target is 129 participants. The study started on 2026-06. Estimated completion is 2028-06.
What interventions are being tested in trial NCT07598734?
The interventions under investigation include: Placebo Tablets (DRUG), Doxepin 6 mg (DRUG), Ramelteon 8 mg (DRUG).
Who is sponsoring clinical trial NCT07598734?
This trial is sponsored by University of Washington, which has 1,048 total clinical trials registered on ClinicalTrials.gov.
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