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NCT07588139 · ClinicalTrials.gov registry record · Phase 1
A Study to Evaluate Dermal Open-Flow Microperfusion and Plasma Pharmacokinetic Study of Multiple Doses of Oral Povorcitinib or Topical Ruxolitinib Cream in Healthy Adult Participants
A Phase 1 study, sponsored by Incyte Corporation.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 24
- Enrollment target
NCT07588139: Recruiting Phase 1 study, sponsored by Incyte Corporation.
NCT07588139 is a Phase 1 study that is actively recruiting participants, run by Incyte Corporation. The registered enrollment target is 24 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (60% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07588139, a Phase 1 study, is actively recruiting participants, sponsored by Incyte Corporation.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 24 participants
- Enrollment target
Study Summary
The purpose of this study is to evaluate the interstitial concentrations using the open-flow microperfusion device and plasma pharmacokinetics following multiple doses of povorcitinib or topical ruxolitinib cream in healthy adult participants.
Primary Outcome
Defined as the maximum observed plasma concentration.
Interventions
- DRUG Ruxolitinib
- DRUG Povorcitinib
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2026-05-18 |
| Est. Completion | 2026-09-19 |
| Phase | Phase 1 |
What NCT07588139 shows while recruiting
NCT07588139 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (60% lower).
The record links to 0 conditions, and to 2 interventions - of which Ruxolitinib is the first listed.
NCT07588139 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07588139 about?
NCT07588139 is a clinical study titled "A Study to Evaluate Dermal Open-Flow Microperfusion and Plasma Pharmacokinetic Study of Multiple Doses of Oral Povorcitinib or Topical Ruxolitinib Cream in Healthy Adult Participants". The purpose of this study is to evaluate the interstitial concentrations using the open-flow microperfusion device and plasma pharmacokinetics following multiple doses of povorcitinib or topical ruxolitinib cream in healthy adult participants.
What is the current status of trial NCT07588139?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 24 participants. The study started on 2026-05-18. Estimated completion is 2026-09-19.
What interventions are being tested in trial NCT07588139?
The interventions under investigation include: Ruxolitinib (DRUG), Povorcitinib (DRUG).
Who is sponsoring clinical trial NCT07588139?
This trial is sponsored by Incyte Corporation, which has 239 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07588139's enrollment target sits among peer trials
24 1520th of 2000 higher than 405 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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