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NCT07583433 · ClinicalTrials.gov registry record · NA
Maneuvers to Reduce Laparoscopic Pain
A NA study, sponsored by Henry Ford Health System.
- Not yet
- Registry status
- NA
- Development phase
- 150
- Enrollment target
NCT07583433: Clinical Trial NA study, sponsored by Henry Ford Health System.
NCT07583433 is a NA study that has not yet begun recruiting, run by Henry Ford Health System. The registered enrollment target is 150 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (89% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07583433, a NA study, has not yet begun recruiting, sponsored by Henry Ford Health System.
- NOT YET RECRUITING
- Registry status
- NA
- Development phase
- 150 participants
- Enrollment target
Study Summary
Laparoscopic surgery has revolutionized surgical care by reducing morbidity and improving post operative recovery. Laparoscopic surgery involves the use of carbon dioxide for insufflation to achieve optimal visualization. There is literature that demonstrates higher insufflation pressures being associated with increased postoperative pain - particularly shoulder pain - and opioid use. The ideal amount of intraperitoneal pressure is still under debate as other studies demonstrate that reduced pneumoperitoneum insufflation has also shown to negatively impact surgeon satisfaction and trended with longer operative time and greater blood loss without impacting pain. Residual intraperitoneal carbon dioxide can also contribute to postoperative discomfort. Studies have shown the effectiveness of various maneuvers in removing residual gas to reduce postoperative pain, such as intraperitoneal saline instillation, pulmonary recruitment, and gas aspiration via smoke evacuator. Despite these advantages, there is a lack of a clear consensus on the optimal method for reducing residual intraperitoneal gas. Conversely, literature has mixed results regarding the true significance in pain reduction. Given the importance of minimizing postoperative pain, reducing opioid requirements, and shortening postoperative recovery time, the investigators propose a prospective, patient-blinded, randomized controlled trial. The investigators aim to investigate whether active gas removal via a smoke evacuator, multiple breath recruitment maneuvers, or no intervention would contribute to lowest postoperative pain. The findings will help identify the most effective method for reducing residual pneumoperitoneum-related pain and thus inform surgical practices and improve patient outcomes.
Primary Outcome
Post-operative pain: Patients will be assessed using the Numeric Rating Scale (NRS) by rating their pain on a scale from 0 (no pain) to 10 (worst pain imaginable) immediately prior to leaving the post-anesthesia care unit, on post-operative day 2, and post-operative day 7.
Interventions
- PROCEDURE Control Group
- PROCEDURE Smoke Evacuation Group
- PROCEDURE Recruitment Breath Group
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 150 participants |
| Start Date | 2026-07-10 |
| Est. Completion | 2028-11 |
| Phase | NA |
What is known before NCT07583433 opens enrollment
NCT07583433 is an interventional study that assigns participants to a tested intervention. The registered 150 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (89% lower).
The record links to 0 conditions, and to 3 interventions - of which Control Group is the first listed.
NCT07583433 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07583433 about?
NCT07583433 is a clinical study titled "Maneuvers to Reduce Laparoscopic Pain". Laparoscopic surgery has revolutionized surgical care by reducing morbidity and improving post operative recovery. Laparoscopic surgery involves the use of carbon dioxide for insufflation to achieve optimal visualization. There is literature that demonstrates higher insufflation pressures being asso...
What is the current status of trial NCT07583433?
This trial is currently not yet recruiting. It is a NA study. The enrollment target is 150 participants. The study started on 2026-07-10. Estimated completion is 2028-11.
What interventions are being tested in trial NCT07583433?
The interventions under investigation include: Control Group (PROCEDURE), Smoke Evacuation Group (PROCEDURE), Recruitment Breath Group (PROCEDURE).
Who is sponsoring clinical trial NCT07583433?
This trial is sponsored by Henry Ford Health System, which has 234 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07583433's enrollment target sits among peer trials
150 661st of 2000 higher than 1,299 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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