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NCT07583186 · ClinicalTrials.gov registry record · NA

Maternal Intake of Eggs and Infant Neurodevelopment

A NA study, sponsored by University of Kansas Medical Center.

Recruiting
Registry status
NA
Development phase
100
Enrollment target

NCT07583186: Recruiting NA study, sponsored by University of Kansas Medical Center.

NCT07583186 is a NA study that is actively recruiting participants, run by University of Kansas Medical Center. The registered enrollment target is 100 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (93% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07583186, a NA study, is actively recruiting participants, sponsored by University of Kansas Medical Center.

RECRUITING
Registry status
NA
Development phase
100 participants
Enrollment target

Study Summary

The fetal brain requires DHA, choline, lutein, and zeaxanthin (L/Z) for development, dependent on maternal intake during pregnancy. However, many pregnant women do not meet daily requirements through diet or prenatal vitamins. Egg yolks are rich in choline, and women who consume eggs daily are more likely to meet the adequate intake of 450 mg/day. A recent study by Christifano et al. found that maternal egg and neuroprotective nutrient intake predicted neurodevelopment at 32 and 36 weeks of gestation. This study aims to determine if fetal neurodevelopment is enhanced among women who consume a prenatal diet emphasizing egg consumption (EGG) versus a healthy prenatal diet education control group (HPD). Women between 12-20 weeks' gestation will be randomized into EGG and HPD groups. The EGG group will receive education on the importance of prenatal choline and egg consumption and be encouraged to consume 10-14 eggs per week. The HPD group will receive education on a healthy prenatal diet. Both groups will be encouraged to take a DHA supplement, and dietary intake of choline, L/Z, and DHA will be collected. Fetal heart rate variability will be measured at 36 weeks gestation and infant EEGs will be conducted postnatally to examine brain function. Increasing prenatal egg consumption is both economical and feasible to boost prenatal choline intake, promote offspring neurodevelopment, and guide prenatal dietary recommendations.

Primary Outcome

Group comparisons will be made between time-domain metrics of fetal HRV (SDNN, RMSSD) between those in EEG vs. HPD groups using a dedicated fetal heart rate monitor.

Interventions

  • DIETARY_SUPPLEMENT Egg Supplementation
  • DIETARY_SUPPLEMENT Healthy Prenatal Diet

Trial Details

FieldValue
Enrollment Target 100 participants
Start Date 2026-01-01
Est. Completion 2028-06
Phase NA
University of Kansas Medical Center

408 total trials

What NCT07583186 shows while recruiting

NCT07583186 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (93% lower).

The record links to 0 conditions, and to 2 interventions - of which Egg Supplementation is the first listed.

NCT07583186 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07583186 about?

NCT07583186 is a clinical study titled "Maternal Intake of Eggs and Infant Neurodevelopment". The fetal brain requires DHA, choline, lutein, and zeaxanthin (L/Z) for development, dependent on maternal intake during pregnancy. However, many pregnant women do not meet daily requirements through diet or prenatal vitamins. Egg yolks are rich in choline, and women who consume eggs daily are more ...

What is the current status of trial NCT07583186?

This trial is currently recruiting. It is a NA study. The enrollment target is 100 participants. The study started on 2026-01-01. Estimated completion is 2028-06.

What interventions are being tested in trial NCT07583186?

The interventions under investigation include: Egg Supplementation (DIETARY_SUPPLEMENT), Healthy Prenatal Diet (DIETARY_SUPPLEMENT).

Who is sponsoring clinical trial NCT07583186?

This trial is sponsored by University of Kansas Medical Center, which has 408 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07583186's enrollment target sits among peer trials

100 840th of 2000 higher than 1,081 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07583186, the US trial registry maintained by the National Library of Medicine. NCT07583186 (mid enrollment · none site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.